We all remember this 2005 hit, right? Well if you thought the clinical title, the heavy lyrics, and the not-so-subtle music video all point towards this song being a tribute to someone who has passed, you were absolutely right. Lead singer of The Fray, Isaac Slade, has said the song was influenced by his experience as a mentor for troubled youth. Isaac connected with one guy in particular, a musician, who was struggling with depression. The verses of the song describe an adult struggling to get through to the guy, while the chorus relays Isaac's own failure to give him the support he needed.