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Updated on Jun 10, 2020. Posted on May 25, 2020

You Can Only Pick One "Grey's Anatomy" Moment Per Season And Sorry, It's Pretty Hard

The "Pick me. Choose me. Love me" speech or Denny and Izzie's relationship?

Here's the deal: Below are several major moments from each season of Grey's. Your job is to choose which moment is the most important and/or your absolute favorite.

🚨Obviously MASSIVE spoilers ahead, too!🚨

  1. Season 1:

    Season 1:

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Season 1:
  1.  
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    Meredith and Derek sleeping together
  2.  
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    The original interns being assigned to Bailey on their first day
  3.  
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    Cristina starting to secretly date Burke
  4.  
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    Addison arriving at Seattle Grace
  1. Season 2:

    Season 2:

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Season 2:
  1.  
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    Meredith's iconic "Pick me. Choose me. Love me" speech
  2.  
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    Everyone trying to save Bonnie and Tom after the train crash
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    The bomb exploding after being stuck inside a patient
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    Izzie and Denny's relationship, plus her cutting the LVAD wire
  1. Season 3:

    Season 3:

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Season 3:
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    Burke and Cristina secretly dealing with his hand tremor
  2.  
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    George's dad sadly dying at Seattle Grace
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    The massive ferry boat crash
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    Burke leaving Cristina at the altar
  1. Season 4:

    Season 4:

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Season 4:
  1.  
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    Lexie Grey arriving as a new intern at Seattle Grace
  2.  
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    Izzie and George becoming a ~couple~
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    Alex dealing with Ava/Rebecca
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    Meredith building Derek the house out of candles
  1. Season 5:

    Season 5:

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Season 5:
  1.  
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    Owen arriving and helping Cristina after she's impaled by an icicle
  2.  
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    Izzie seeing Denny and learning that she has cancer
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    Derek and Meredith getting married via Post-it Note
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    Meredith learning that John Doe is George
  1. Season 6:

    Season 6:

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Season 6:
  1.  
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    Seattle Grace and Mercy West merging
  2.  
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    Izzie leaving Seattle Grace and Alex
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    Derek becoming chief of surgery
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    The hospital shooting and EVERYTHING that came with it
  1. Season 7:

    Season 7:

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Season 7:
  1.  
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    Owen's trauma certification workshop
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    The musical episode
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    Callie and Arizona getting married
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    Meredith messing with her and Derek's Alzheimer's trial
  1. Season 8:

    Season 8:

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Season 8:
  1.  
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    Meredith and Derek officially adopting Zola
  2.  
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    Teddy marrying Henry before he sadly died
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    April having sex with Jackson but failing her boards
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    The plane crash and Lexie dying
  1. Season 9:

    Season 9:

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Season 9:
  1.  
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    Mark tragically dying after the plane crash
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    Renaming the hospital "Grey Sloan Memorial Hospital"
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    Bailey and Ben getting married
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    Alex telling Jo that he loves her
  1. Season 10:

    Season 10:

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Season 10:
  1.  
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    Jackson and April eloping
  2.  
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    Callie and Arizona getting back together and wanting another baby
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    Cristina and Meredith dancing it out before Cristina leaves
  4.  
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    Cristina's "He's not the sun. You are" speech to Meredith
  1. Season 11:

    Season 11:

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Season 11:
  1.  
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    Maggie arriving at Seattle Grace and telling Meredith she's her sister
  2.  
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    Amelia moving to Seattle and trying to save Nicole Herman's life
  3.  
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    April and Jackson tragically losing Samuel
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    Derek dying after saving a family on the side of the road
  1. Season 12:

    Season 12:

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Season 12:
  1.  
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    Bailey becoming chief of surgery
  2.  
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    Callie starting to date Penny
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    April and Jackson getting divorced, and April learning that she's pregnant again
  4.  
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    Amelia and Owen getting married
  1. Season 13:

    Season 13:

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Season 13:
  1.  
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    Jo revealing that she's actually married already
  2.  
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    Maggie's mom dying
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    Meredith and Riggs starting to date
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    Owen learning that his sister, Megan, is actually alive
  1. Season 14:

    Season 14:

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Season 14:
  1.  
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    Meredith winning a Harper Avery Award
  2.  
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    Arizona moving to New York City and reconnecting with Callie
  3.  
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    Jo and Alex getting married
  4.  
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    April marrying Matthew and leaving Grey Sloan
  1. Season 15:

    Season 15: