Written by: Gigi Levangie, Jessie Nelson, Steven Rogers, Karen Leigh Hopkins, and Ron Bass
Directed by: Chris Columbus
What it's about: Jackie Harrison (Susan Sarandon), a woman dying of terminal lymphoma, comes to terms with her children (Jena Malone and Liam Aiken) being raised by her husband's girlfriend Isabel Kelly (Julia Roberts).
When you'll start crying: Isabel tearfully confesses that her biggest fear is Anna reaching her wedding day and wishing her mother were there. Jackie, also crying, shares her fear that Anna won't miss her at all.
When you'll totally lose it: At Christmas, Jackie reminds her kids that even though she will soon be gone, she'll be with them as long as they remember her.