Andy Cohen firstly asked Karlie how she felt when the moment went viral. She responded: "Well, listen, I was honoured to be one of the first memes of the decade. Honestly, the real tragedy of this whole thing is that no one is talking about how terrible that dress was!"
Andy then steered the conversation back to the Kushners and straight-up asked Karlie whether or not her political views align with the rest of the family's.
She responded: "Andy. I'm sure I'm not the only person in this country that does not necessarily agree with his family on politics."
"I voted as a Democrat in 2016, and I plan to do the same in 2020," she added.
Karlie went on to say that she's a proud activist on issues that directly conflict with Trump's agenda.
Andy then highlighted the fact that Karlie met Josh in 2012, adding that she's "been through a lot" with him, including converting to Judaism.
"I met my man in 2012. I was 19 years old," Karlie responded. "It was 2012. It was a different world. And my man and I have been through a lot together. I'm so proud that he's my partner. It's not been easy, but it's worth it and I'd make that same decision a million times again."
It's not the first time Karlie has addressed how difficult it's been to deal with the connection to Trump, especially under the glare of the public eye.
You can watch the full interview with Karlie Kloss here.