Michael Seater as Derek Venturi
He just directed a film called People Hold On to be released online May 31, and has starred in TV series such as Bomb Girls and Murdoch Mysteries in the years since being the title character of Life With Derek.
Ashley Leggat as Casey MacDonald
She'll be starring in Michael Seater's indie film People Hold On this May, and has had roles on Criminal Minds and Good Witch.
Jordan Todosey as Lizzie MacDonald
She currently stars on the Netflix series Between, played Adam Torres on Degrassi: The Next Generation, is a skateboarder, singer, and photographer.
Shadia Simmons As Emily Davis
She hasn't starred in anything since LWD, but she currently runs Star Acting Studios, which provides coaching and education for kids who want to get into acting and the arts.
Daniel Magder as Edwin Venturi
Since his Disney Channel days, he's had roles on Kroll Show and the Canadian show Mudpit.
Joy Tanner as Nora MacDonald
She's had roles on Degrassi: The Next Generation and Skins since playing Derek's stepmom, and she's a writer and mom IRL.
John Ralston as George Venturi
Since playing Derek's dad, he starred in several seasons of Degrassi and has had a huge role on the current Canadian TV series Bitten.
And Ariel Waller as Marti Venturi
She hasn't starred in anything since Life With Derek.