thecureisnow

thecureisnow
     
The Cure Is Now is a national, non-profit organization dedicated to eliminating acquired, congenital, and developmental diseases.
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  • Overview:

    Overview: Hello, if this is your first time here this page will help guide you through properly informing yourself about The Cure Is Now and how to best interact with this Website and our charity. The site is broken down into various sections and we encourage you to please read through as much of it as possible. This will answer the majority of your questions. The driving forces behind the cure is now are the realization of something known as the technological singularity. There is an event that will change the world more so than major breakthroughs like the Internet, industrialization, democracy, flight, or other paradigm shifting social evolutions. This event known as the technological singularity will bring forth changes for human kind that will address some of our most fundamental needs in ways that have never been before possible. The Cure Is Now is an organization made up of individuals, as well as supporters who realize that these technologies will greatly impact medicine. Research has shown that several groups of thus far dissimilar diseases can be potentially addressed in ways that have never before been conceived and find the long sought after cures that are still wishful thinking today the cure is now seeks to address the very concept of attacking these diseases with these new emerging technologies. So if you’re looking for an explanation as to why The Cure Is Now target one simple disease but rather several of them it’s because we are not believers that the way to cure a disease is through the conventional pharmaceutical and medical methods used thus far. We believe that there will be a wholesale slew of radically advanced new technologies which will address the common threads in many of these failed diseases. The Cure Is Now subscribe to what we call the root level approach. The root level approach quite simply states that a convergence of several new technologies of “singularity evolved” advanced technology will address the hurdles in thus far incurable diseases. These technologies include: • Artificial General Intelligence & Robotics • Nanotechnology & MEMS • Synthetic Biology, Biotechnology, & Bioinformatics • Human-Machine Interfaces, Brain-Machine Interfaces & Neuroscience • Networks & Super Computing Systems • Genomics & Sequencing • Materials Science & Bioengineering In conclusion The Cure Is Now is not tackling the insurmountable problem of trying to simultaneously find the cures to roughly 2 dozen incurable diseases. Rather it is advocating for the education of the public on the benefits that research into the above fields will benefit. The Cure Is Now will be instrumental in causing both public and private institutions to apply these technologies in their infancy stages to finding solutions to these diseases. That is why you are here at this exact moment reading this. The next step for you is to become informed. Ultimately, our objective is to expand internationally and help guide the application of the singularity, which we believe will have many wonderful benefits to medicine. This will take money and we ask that you Donate Now.  

    thecureisnow 10 months ago respond

  • Mission Statement

    Mission Statement The Cure Is Now is a national, non-profit organization dedicated to eliminating acquired, congenital, and developmental diseases. Our cornerstone philosophy is to use a convergence of emerging technologies to combat diseases at the root level. Operational programs include: awareness campaigns, education initiatives, and scientific research. The objective is to eradicate disease as a major health problem by managing programs designed to further scientific development. We need the cures. The time is now. The Cure Is Now Vision Statement The Cure Is Now envisions the discovery of cures for thus far incurable diseases, by establishing a world-class research facility with dedicated scientists that are leaders in their respective fields. Through the application of emerging advanced technologies, The Cure Is Now facilitates breakthrough medical discoveries that will give us the cures. Values Statement The Cure Is Now subscribes to the following corevalues: innovation, synergy and discovery. We are leading an international collaboration of scientists researching emerging advanced technologies to find cures for what are currently incurable diseases. As a catalyst, The Cure Is Now is bringing together the greatest minds in the world in creative and singular ways. This research will bring about breakthrough medical treatments for patients everywhere.  

    thecureisnow 10 months ago respond

  • Elevator Pitch:

    Elevator Pitch: Why do we need The Cure Is Now? The Cure Is Now is a science and technology advocacy and research organization. Applying new technology to a variety of medical needs is our goal. One of our many programs is to develop, adapt and converge disparate and emerging technologies in brilliant and innovative ways that result in breakthrough medical solutions. There is a social routine where unfortunate friends and relatives of disease stricken loved ones rally around a cause centered at “stamping out” or “beating a disease.” The Cure Is Now additionally believes in how something called the Technological Singularity will yield new science that will give us the tools to eliminate many diseases. We are not so bold as to think that we can solely tackle all of the diseases in the world, when thousands of such organizations have failed to do so collectively - it is precisely the opposite. We are the only medical research & advocacy organization with specific programs that are developing the technologies that other organizations will be able to utilize to achieve their individual missions. Just like small pox and polio were eradicated because of technological advancements, other diseases will eventually be eliminated too. The Cure Is Now admires and respects the efforts of the multitude of non-governmental organizations and charities, which support and rally the victims and associates of whatever particular disease has affected their lives. We also don’t believe there is an urgent need for yet another cancer or AIDS or similar type of charity pop up because the many thousands of organizations that are currently out there do more than enough to address the issues that they are focused on. The Cure is Now does not believe in duplicating the efforts of these fine, world-class institutions, that is why The Cure Is Now is an established leader in applying groundbreaking and “Singularity Technologies” to the medical field. No other organization matches our programs and operations, nor offers the unique solutions we do. This is not because others haven’t wanted to find cures. What makes The Cure is Now’s situation is different in that breakthrough technological opportunities are just now unfolding before us, and the next several years ahead will be the fulcrum where a fundamental paradigm-shift occurs and The Cure is Now will take advantage of this. For example, imagine the world many hundred of years from now where mankind has become sufficiently advanced and a great number of human ailments and diseases have been eliminated via technology-based cures. Many of today’s epidemics like cancer, AIDS and Alzheimer’s disease will be treated with nothing more than a routine trip to the doctor’s office. This website offers very clear, detailed and unambiguous information including specifics on our plan and the details of programs that will be utilized to achieve the goal in our mission statement: the elimination of disease through technology. We Need The Cures, The Time Is Now, The Cure Is Now!  

    thecureisnow 10 months ago respond

  • Founder’s Message

    Founder’s Message Hello. My name is AnnMarie Santiago. There are generally 2 main reasons why people get involved with medical research. First, because of a personal experience where they themselves, a family member, or a friend, has been afflicted with a chronic disease, or second, because they realize we have the technology right in front of us to rid the world of many diseases forever. Both of these reasons are why I founded The Cure Is Now. I feel that with a grassroots approach to networking, funding, and research, we can move forward and make history of many of these diseases that plague us. Social Networking will be used to reach out to those affected directly and indirectly by disease such as cancer or AIDS. The average person’s phone has between 50 – 70 contacts. If a loved one develops cancer and you reach out to those contacts in your phone, or even the contacts on your Facebook page or email address book, these people are more likely to donate to the cause, and then they will contact the people they know, and before you know it you have a ripple effect. In today’s technological world it is effortless to contact someone, which is something we need to take advantage of in our awareness and education campaigns. The strongest connections are made through direct interaction. In an effort to show individuals that these illnesses can effect their own lives, The Cure Is Now is taking a street level and personal interaction program based on individual needs, thus creating small social connections within communities which will soon add up to large numbers.  

    thecureisnow 10 months ago respond

  • Expert Opinions

    Expert Opinions We are very interested in what the experts have to say. You can be in any relevant field, from the medical industry to engineering, general technology, or other sciences including expertise in: nano technology, biotechnology, computer technology and information technology. We are also interested in non medical opinions as well, for example: if you or someone you know has been affected by disease, we want to hear your story. The Cure is Now consults with experts in their respective fields regarding all aspects of our operations. Additionally, we are seeking information for early disease diagnosis, therapy selection, patient recruitment into clinical trials, predicting predisposition to disease and providing valuable information for the design of new treatments. Each consultation should include an ‘expert opinion’ document, in which authors are asked to provide their personal view on the current status and future direction of the research discussed. Please send us your expert opinion to: info@thecureisnow.org and place “expert opinion” in the subject line, followed by your topic.  

    thecureisnow 10 months ago respond

  • Multimedia

    Multimedia https://www.youtube.com/watch?feature=player_embedded&v=HQ9_lEZx6rE https://www.youtube.com/watch?feature=player_embedded&v=uANNZMFiBn4 https://www.youtube.com/watch?feature=player_embedded&v=2E-qEAHy3ew https://www.youtube.com/watch?feature=player_embedded&v=rpspGPr4gjM https://www.youtube.com/watch?feature=player_embedded&v=SMmIGuWQ_rc

    thecureisnow 10 months ago respond

  • Philosophy Of T.C.I.N.

    Philosophy of T.C.I.N. Medical Research is at the beginning of a second great revolution. For decades medicine has inched forward while technology takes giant leaps year after year, and this is only going to get faster. As time has revealed, medicine is continuously enhanced via technology. So instead of trying to invest more resources and funding into traditional research methods, The Cure is Now will catalyze innovative solutions to our current health care issues by supporting research that lies between technology and medicine. The Cure is Now is dedicated to bringing better treatments, faster, through technology. Research Methodology———————————- The Cure Is Now has a broad and ambitious goal of discovering cures for acquired, congenital and developmental diseases. We will achieve this through focusing our efforts on research that drills down to the root level via these four research approaches: • Curiosity Driven Research • The Cure is Now will fund scientific investigators and their teams who are called to research aspects of disease pathology, biological systems, or biotechnological mechanisms. This type of research will yield enhanced understanding, deepened knowledge, unpredictable, long term, and widely-dispersed social and medical benefit. • Applied Research Research funded by The Cure Is Now will lead to direct medical applications such as enhanced treatments, targeted gene therapy, technology-based solutions and more. • Synergistic Research This unique kind of research will be aimed at linking and connecting different kinds of science and technology. For example, how can stem-cell research be connected with brain-machine interface technology or how can nanotechnology be employed in Alzheimer’s research? TCiN will be the lines in between the dots. These kinds of questions will be answered by scientists at The Cure Is Now. • Not-yet-known Research The Cure Is Now understands that the kind of research it will support undoubtedly will lead to entirely new fields and forms of research. The Cure Is Now will selectively support these as well. Research Management————————————- Efficiency is an important part of TCIN’s philosophy. The Cure is Now is interested in increasing the efficiency and effectiveness of research. As such, it is attempting to be as efficient as possible by eliminating dysfunction, politics and unproductive work. Inefficiency tends to plague research. Many people do not perform to their potential, slowing progress through insufficient productivity, failure to cooperate with colleagues and even sabotage of other’s research or producing useless results. In order to spur development of new cures, and to do so where other organizations have failed, a system of communication, monitoring and incentives must be implemented to maximize productivity and efficiency. The most obvious source of inefficiency is the case of an employee not doing the work for which they have been hired. The solution is equally obvious: replace the employee with someone else. When people are rewarded for working with compensation and continued employment, and face the consequences of demotion or termination for failure to work, they tend to work hard; if they don’t, someone else will. Often times, workplaces are dysfunctional due to “politics” or other situations in which employees, instead of cooperating towards a common goal, pursue their own interests, to the detriment of other employees and the organization as a whole. The solution here is to have an aware and well-informed management presence to monitor the dynamics of the workplace, identify inefficiencies caused by dysfunctional interactions between employees, and to incentivize the culpable parties to alter their behavior (or replace them with more cooperative employees if necessary). Some inefficiencies may not be due to the actions of any individuals, but may be due to a structural deficiency in the system in which they work. For example, two departments may be doing redundant work on the same project, two departments which need to work together may encounter institutional obstacles to doing so, or two departments which could collaborate may not do so because they are not even aware that they have a potential synergy. Again, management needs to be aware of these situations when they arise (or design the system to prevent them from arising) and modify the system to address them. But by what standard is efficiency to be measured? Although it would be great to measure it by number of diseases cured per year (for example), it would not be practical due to lengthy timescales involved and the fact that, due to the unpredictable nature of research, a treatment may turn out to be ineffective through no fault of those who developed it. In industry, efficiency is measured by profits, which are not necessarily correlated with how many lives a product has saved or how much it has improved the standard of living; in academia, efficiency is measured by publications, which leads researches to focus on quantity instead of quality; and governments give grants to research, but very few legislators come from scientific backgrounds, and their well-intentioned but uniformed decisions, combined with the actions of some who only wish to score points with their constituents, mean that funds are not always allocated in the most efficient manner. The Cure is Now proposes to solve this problem by having a leadership composed of scientists. Together, these experts can agree upon reasonable and desirable goals whose accomplishments would lead to substantial advancement of progress towards understanding and curing diseases. Instead of being given vague and informal assignments, employees would be given clear, specific contracts. If each employee fulfilled their contract, then their work would lead to the accomplishment of the goals set by the scientific leadership. By having scientists set goals and then implementing a system in which researchers work efficiently to achieve those goals, The Cure is Now aims to drive new advances in the work of curing disease. Root-Level Approach——————————————- Forget what you think you know about diseases. For legal reasons we cannot give you medical advice, only your doctor can. But we want you to think about research and finding cures in a whole new light. Research is what ultimately drives medical discoveries, and it is that medical research which must undergo a fundamental paradigm shift. This will be caused by The Singularity. Below you will find a list of diseases that may seem as though they have nothing to do with one another. But if you look closely, they share the common thread that there are no known cures, but also, they share root-level similarities. Billions of dollars worth of research money has gone into curing these diseases, but to no avail. That is because we have been using the past 60 years worth of technology to tackle them, and trying new techniques has been far too slow. You may look at this list and wonder, how do you intend to cure this vast number of diseases at the same time when massive efforts have been made just to individually cure them? Well, there is a difference to our approach. We will converge newly emerging technologies. We are not suggesting that we can guarantee a magic pill, delivered tomorrow. We do believe, however, that over the next several years, but hopefully fewer, there will be an overlap of different types of technologies, making the currently impossible, possible. A fundamental paradigm shift away from the purely pharmaceutical, and conventional western medical practices needs to be evolved. The Cure Is Now wants to aggressively fund research and education/awareness initiatives that will shape and hasten these cures. Nanotechnology, biotechnology, information technology, cognitive sciences and several other disciplines will merge in ways never before possible. We know that what we are suggesting may not be easy to ponder. The Cure Is Now is a group of highly motivated, talented, capable, individuals who will push for the cures. The process works like this: first there is general research, which leads to drug development, then scientists move on to clinical research/trials, then possible FDA approval, thus allowing a drug to become available for patients. This process typically costs over $1 billion, not to mention several years. We believe we can streamline this process tremendously, yet without cutting corners on any person’s safety. If you would like to see this happen, please donate now. List of some diseases we may be able to cure: • Macular Degeneration • Liver Cirrhosis • Muscular Dystrophy • AIDS/H.I.V. • General immunity • Cardiovascular • Cancer • COPD (Chronic Obstructive Pulmonary Disease) • Degenerative Disc Disease • Alzheimer’s • Osteoarthritis • Rheumatoid Arthritis • Osteoporosis • Skin aging • Cell & tissue transplant • Progeria • Dyskeratosis Congenita • Idiopathic Pulmonary Fibrosis • Cri-du-chat syndrome • Down Syndrome • Fanconi Anemia • Tuberous sclerosis • Werner Syndrome Technological-Singularity————————————— The Cure Is Now believes that the root level approach will be powered by a phenomenon called the singularity. After much debate and deliberation we have concluded that in order for an individual to be able to understand for themselves what the technological singularity will be, and how it will affect medicine, is to understand it for yourself through research. We feel that rather than preaching to you we prefer to lay out the facts as they are, provide you with resources for further reading and allow you to draw your own conclusions based on expert opinions in the field. This route is the most honest and obvious approach. Below we have provided you with some links to begin your journey on the understanding of the singularity, and we ask that when you read it you think about how it will apply to medical research. You will find an endless supply of information on the Internet regarding this topic. We urge you to educate yourself on this topic. This is only the beginning, and The Cure Is Now is actively pursuing the most promising endeavors. Personalized Medicine————————————— The Cure is Now is very interested in advancing personalized medicine approaches to health care. Personalized medicine takes advantage of the knowledge we have garnered thus far from genetics, tissue regeneration, stem cell research, cellular markers, hormones, cell signaling pathways and many others in order to apply them to treating individual patients in the most effective way possible. The Cure is Now seeks to positively disrupt the current medical system through supporting innovative, personalized medical practices, which allow individuals to receive focused care and access to the most cutting edge medical technologies available. The Cure is Now encourages true partnerships between patients and doctors and envisions a future where doctors spend much more time with their patients, and patients receive the best possible care for their lifestyle, diet, their body and physical make up.  

    thecureisnow 10 months ago respond

  • Science Departments:

    Science Departments: Artificial Intelligence————————————— For the past century, progress in medicine has been driven by the discovery of narrow, focused treatments for acute illnesses. Although this approach initially yielded spectacular results, medical progress has, in recent years, begun to slow, indicating the need for a new paradigm. This is because the most prevalent causes of death and illness are no longer simple diseases caused by infection or dysfunction in a single gene. Instead, the diseases faced by modern society are the result of complex interactions between networks of genes, cells, organs or even people. A new, systems-based approach is needed, but this will require gathering and analyzing unprecedented amounts of data. A task of this magnitude and difficulty would, in past eras, be impossible. However, the imminent development of smarter-than-human artificial intelligence will make this previously inconceivable process a reality. By taking advantage of this emerging area of research, The Cure is Now aims to develop novel treatments and cures for previously untreatable illnesses. Narrow Artificial Intelligence Great advances in narrow artificial intelligence have been made in the past decades. First, computers mastered checkers. Then, computers became better than humans at chess. Now, computers are even capable of answering trivia questions on game shows. There is great potential for this technology to be applied to medicine. For example, a doctor could input a patient’s symptoms into a computer, which would suggest possible diseases that the doctor might not have considered. Or, scientists could use computers to figure out results from experiments, allowing humans to spend more time on advanced analysis. Alexander D. Wissner-Gross conducts research in artificial intelligence on a massive scale. His recent research project includes a planetary scale computing model for electronic trading. Artificial General Intelligence Artificial general intelligence would entail the creation of a computer-based intelligence at least as smart as a human. The benefits of the this achievement would be twofold: first, as a peer with whom people could consult; second, the accomplishment of this goal would give great insight into what allows us to think and comprehend. Dr. Itamar Arel is working on pushing the edge of Artificial General Intelligence forward. Click here to learn more about Dr. Arel’s research projects. Ben Goertzel conducts research in artificial intelligence and uses patterns and models of how humans think and applies them to computer learning programs. Click here to lean more about Ben Goertzel’s research projects. Consciousness Studies The brain is composed of many simple parts, but together they form the most complex entity in the world: the human mind. What is consciousness? What makes thinking possible? What enables us to be sentient? These are the fundamental questions of the brain. Jeff Lieberman, co-host of Discovery Channel’s Time Warp is currently conducting research in in consciousness. Lieberman explores the connections between the arts, sciences, education, passion, creativity, and the potential future of human consciousness. Robotics A major limit on medicine is the accuracy and stamina of human workers. A human can only spend a few hours working before having to rest, and if the task is repetitive, they are likely to make mistakes. A robot, by contrast, can work all day with perfect accuracy. Therefore, robotics can be used to perform many tedious parts of research, while at the same time making the process more efficient. In addition, humans have imperfect perception and are not always precise. Robotics can be used, for example, in surgery, eliminating the possibility of errors and mistakes. Biotechnology—————————————- Bio-Engineering Making a new discovery about a disease is just the first step to finding a cure. Further work must be done to develop a treatment and then optimize the treatment for improving human health. Things that would require such fine-tuning might include: maximizing a drug’s affinity to its molecular target, minimizing side-effects from the drug binding improper targets, increasing the efficiency of the delivery of the drug to the affected tissue, and altering the pharmacokinetics of the drug to create a workable dosage schedule. The field of bio-engineering uses the principles of engineering to address these challenges. Synthetic Biology Technological progress in the 1800s was driven by engineering in the field of chemistry and steam power. Progress in the 1900s was driven by engineering in electronics. Progress in the next century will be driven by engineering in biology. By creating standard biological components and manipulating biological systems like machines, synthetic biologists are laying the ground for the era of progress. Dr. Matthew Putman is researching synthetic biology. Specific potential therapies in this area include rapidly setting polymers for extreme wound treatment and nanosystems for precise drug delivery. Click here to learn more about Dr. Putman’s research projects. Computing————————————————- Supercomputing The diseases most common today are often the most complex. It is unlikely that a simple solution will be easily found. Instead, it will be necessary to collect, analyze and integrate large amounts of data in order to find cures. It is not simply a matter of throwing resources at a problem, however. New computational techniques must be developed to carry out large-scale computing as efficiently as possible. Alexander D. Wissner-Gross conducts research in artificial intelligence on a massive scale. His recent research project includes a planetary scale computing model for electronic trading. Networking Many large computing resources do not consist of one large computer; instead, they are composed of many small computers linked together. Although this approach allows the construction of an easily-upgradable computing center using publicly available parts, it has some disadvantages. The connections between the computers make management more complex and potentially introduce a new bottleneck that could slow down the entire system. New networking techniques could help avoid those potential problems. Quantum Computing Today’s computers are based on silicon transistors. Making the transistors progressively smaller has allowed more and more powerful computers to be developed. Experts anticipate, however, that within the next 10 years we will reach the physical limits of how small transistors can be made. To continue making faster computers, a new approach will be necessary. Scientists are now exploring ways of using the quantum properties of particles to do computation. If such a computer were developed, even a small one, it could rapidly do computations that would take an ordinary computer centuries to complete. Neuro-Computing The human brain contains billions of cells, with trillions of connections. Due to its complex nature, it is capable of extraordinary computational power. In fact, it is probably more powerful than the world’s fastest supercomputer—even though the latter takes up an entire building. Clearly, we have a lot to learn from the human brain. Shaped by billions of years of evolution, it is more powerful and efficient than the computers we have spent mere decades developing. The field of neuro-computing applies lessons from neuroscience to help improve computers. David Eagleman does research in neurology and envisions a future where novel sensory inputs can be connected to the brain. Click here to lean more about Dr. David Eagleman’s research projects. Ben Goertzel conducts research in artificial intelligence and uses patterns and models of how humans think and applies them to computer learning programs. Click here to lean more about Ben Goertzel’s research projects. Ed Rosenfield has written multiple books on neurocomputing. Biocomputing Smartphones are always getting smaller and more powerful. But is it possible that there is an even more powerful computer that is so small you need a microscope to see it? Indeed, it is, as a cell is really a computer. Although seemingly simple on the surface, every cell must constantly monitor its environment, taking in thousands of inputs, from hormonal signals, to nutrition status, to signs of infection, and integrate all that data to decide how to act. The field of biocomputing seeks to harness the naturally-ocurring data processing and computational abilities of biological organisms. Systems Modeling The human body is composed of many intricate systems, such as the nervous system, the cardiovascular system and the respiratory system. The complexity of these systems makes it difficult to determine the cause when they malfunction. Systems modeling uses mathematical and computational techniques to simulate biological systems, enabling scientists to better understand pathologies and develop treatments. Alexander D. Wissner-Gross conducts research in artificial intelligence on a massive scale. His recent research project includes a planetary scale computing model for electronic trading. Tanya Petrossian does research in bioinformatics and systems biology. Bioinformatics The analysis of biological information is undergoing a revolution. It took decades to sequence the first human genome; now, it is possible for a single lab to produce more sequence data in a single day than was produced by every lab in the world during the first 30 years of sequencing. Despite the deluge of data, we have still not witnessed the revolutions in medicine expected from the availability of massive amounts of sequencing. This is because data is not enough: we must also analyze the data to find out its meaning. The new field of bioinformatics is focused on developing new techniques of data analysis in order to gain a better understanding of biological systems and diseases. Tanya Petrossian does research in bioinformatics and systems biology. Russell Hanson is currently involved with bioinformatics research. Click here to lean more about Russell Hanson’s research projects. Genetics——————————————————— The genome is the one component uniting the countless number of cells in the body. No matter how disparate their function or appearance, every cell is controlled by the genome. However, there are downsides to this level of control. A person may be born with a genetic disorder, such as cystic fibrosis or Huntington’s disease which cuts their life short or causes severe disability. Even if a person is born with a perfectly healthy genome, the copies of their genome in each cell may be mutated over time. These mutations can lead to illnesses, the most prominent of which is cancer. Therefore, The Cure Is Now is dedicated to the study of genetics, in order to determine the ways in which genes control cells (with an eye towards finding potential targets for intervention in case of disease) and methods to protect the genome from damage and to repair any pathologies, whether they are inherited or arose spontaneously. 19 Jun Immuno-Therapy The immune system is one of the most sophisticated and powerful parts of the human body. When a new pathogen enters the bloodstream, immune cells quickly develop antibodies that bind to the pathogen more tightly than any molecule that humans are capable of engineering, and they do so more quickly than any lab could design such a molecule. Such a powerful system would have obvious applications towards fighting noninfectious diseases, such as cancer. On the other hand, dysregulation of the immune system is responsible for autoimmune disorders such as type I diabetes. Therefore, exploring ways in which the immune system can be harnessed, stimulated or, if necessary, suppressed is an important area of research. Over time, some diseases, such as cancer, Alzheimer’s and rheumatoid arthritis, increase in prevalence. Curing these diseases would enable senior citizens to pursue a happy, healthy and independent lifestyle. Aubrey de Grey is one of the leading visionaries in research on age-related diseases. His achievements include the enumeration of the types of damage that cause age-related diseases and the development of the Strategies for Engineered Negligible Senescence (SENS), which address each type of damage. The types of age-related damage identified by Aubrey de Grey are: • Cell loss and atrophy: repairing this damage would lead to a cure for osteoporosis and the loss of strength in the elderly. • Cell mutations and epimutations: repairing this damage would lead to a cure for cancer. • Mitochondrial mutations: repairing this damage would cure age-related degenerative disease, as well as hereditary diseases, such as Leber’s hereditary optical neuropathy. • Accumulation of intracellular junk: repairing this damage would lead to cures for macular degeneration and Alzheimer’s disease. • Accumulation of extracellular junk: repairing this damage would also contribute to a cure for Alzheimer’s; it would also help reduce the prevalence of cardiovascular disease. • Cellular senescence: repairing this damage would improve joint health and help treat type II diabetes. • Extracellular crosslinks: repairing this damage would help treat cataracts and improve mobility in the elderly. Most therapies targeted towards these diseases merely treat the symptoms, while leaving the damage that is the underlying cause untouched. Ultimately, such therapies are severely limited in their ability to permanently and profoundly treat disease. The Cure is Now aims to repair the damage at the root of these diseases to produce true cures. Click here to lean more about Dr. de Grey’s research projects. Silvia Gravina studies epigenomic mutations. The epigenome consists of modifications to the nucleotides that make up the genome. The pattern of these modifications influences which genes are expressed, at what times and at what levels. If they become less organized with age, then the intricate pattern of gene expression that ensures health may be disrupted. Studying how the epigenome changes with age may help to treat diseases in elderly individuals. Bill Andrews studies the regulation of telomere length. Telomeres are stretches of DNA sequences at the end of each chromosome that protect it from damage. With each cell division, however, the telomeres get shorter. If they get too short, the cells may stop dividing; if they do keep dividing, then the rest of the genome, no longer protected by telomeres, is vulnerable to damage. Either way, the shortening of telomeres appears to be associated with a decline in health in the elderly. There is an enzyme, called telomerase, which lengthens telomeres in humans, but its activity is normally too low to prevent telomere shortening. Currently, Bill Andrews focuses on finding drugs to increase the activity of telomerase and restore telomere length. The Cure is Now is interested in supporting Bill Andrews in his research due to its applications to treating multiple diseases. Click here to lean more about Dr. Andrews’ research projects. Brandon Milholland studies the role of DNA damage and mutation in the aging process. At birth, every cell in the body has an identical copy of the genome. Every time a cell divides, however, there is an opportunity for errors to be introduced. Over decades and many cell divisions, these errors can accumulate. The result is that in old individuals, every cell may have a different copy of the genome, each with its own set of errors. These mutations can cause cells to decline in function, but the most pressing consequence is the possibility that a cell may receive a mutation that causes it to become cancerous. Studying how cells become mutated may help in developing ways to treat or even prevent cancer and other age-related diseases. Brandon Milholland serves as The Cure is Now’s Research Coordinator to identify promising fields of research and possible collaborations between other scientists working for The Cure is Now. Click here to lean more about Brandon’s research projects. Gene Therapy In the past, treatments for diseases have consisted of manipulating the cellular and physiological environment, while leaving the genome unchanged. While this approach has proved effective for many diseases, especially those that result from external factors, such as infection, it falls short when applied to diseases whose root cause lies in the genome. The result is that many people, born with genetic diseases through no fault of their own, have had few or no treatments available to them. Recent advances have made it possible to manipulate the genome of human cells, and there is now hope that debilitating genetic diseases will be cured in the near future. Systems Biology The components of biological systems do not exist in isolation. Rather, they are constantly interacting with each other. Previously, biology was studied in a reductionist manner, one piece at a time. As our understanding has increased, however, it has become apparent that further advances require an integrationist approach, in which systems as a whole are studied. It is only by studying the complex networks of interaction that we can begin to understand how organisms truly work, and how to cure complex diseases. Tanya Petrossian uses computational and biochemical techniques to study the methyltransferome, the system by a chemical signal, the methyl group, is transferred between different molecules in the cell. Human-Machine Interfaces————————————— Computers existed for decades, but did not become popular until user-friendly interfaces were developed. Computing power has doubled ever 18 months since then, but user interfaces have not undergone such frequent revolutions. Therefore, it is possible that we are only using a fraction of the computational power available to us. New advances in ways to interface with computers will allow our ability to utilize computers to advance by leaps and bounds. David Bychkov is working on sensors that can enhance our connectivity to the world. He is developing products that measure our health, emotional and vital sign information which is then easily transmitted to wireless devices such as smart phones. Click here to lean more about David Bychkov’s research projects. Brain Machine Interface The most direct way of communicating with a computer would be through an interface directly with the brain. This would allow people to engage with machines more efficiently than ever before, but the benefits wouldn’t stop there. Brain machine interfaces would open avenues of communication for people who previously had none. Imagine, for example, people with paralysis, being able to direct robotic limbs. Even those in a coma, who previously would have had no way to communicate with others, would be able to talk again. David Eagleman does research in neurology and envisions a future where novel sensory inputs can be connected to the brain. Click here to lean more about David Eagleman’s research projects. Electronic Prosthetics Every year, thousands of people lose limbs to disease and injury. Transplants are hard to come by and involve the risk of rejection, and while artificial limbs are available, they are often cumbersome, move unnaturally, and lack feeling. Therefore, it would be desirable to create electronic prosthetics that could receive commands directly from the patient’s nerves and deliver sensory data back along the same route. Short of regrowing the lost limb, this would be the best replacement. Sheila Nirenberg studies how light-sensitive microchips can be connected to the brain to allow blind people to see. Click here to lean more about Dr. Nirenberg’s research projects. Material Sciences——————————————- Mass production has made it possible to manufacture many materials in large quantities, but few of these materials are suitable for use in medicine. Although it would be great to be able to replace lost skin or worn-out joints with synthetic equivalents indistinguishable from the original, current technology offers only crude imitations of naturally occurring biological materials. Therefore, new innovations in material sciences could have the potential to revolutionize medicine. Dr. Christopher Bettinger is using material science in his work to develop novel medical implants which could revolutionize weight loss, chronic pain and infections. Nanotechnology————————————————- Much of the technological progress of the past half-century has been driven by ever-increasing miniaturization. Every 18 months, the amount of space occupied by electronic components has been reduced by half. The small size of computers has made possible life-extending technologies such as the pacemaker. Now, computers are not just microscopic (measured in millionths of an inch) but nanoscopic (measured in billionths of an inch). This extreme miniaturization could allow for the development of revolutionary new medical devices. MEMS MEMS, or microelectromechanical systems, is the field of small, electricity-powered, mechanical devices. For nanotechnology to work, it is important to be able to use electronics to physically manipulate objects at the nano-level. That is where MEMS comes in, allowing computer instructions to be transferred to nano-sized machines. Neuroscience————————————————- The brain is the body’s most important organ, but also the most complex. This complexity has hindered treatment for many diseases. However, advances in neuroscience may change the situation. The brain, our central and peripheral nervous systems are our command centers. By applying treatments and novel solutions to the command centers of our bodies, therapeutic interventions could work much more effectively and rapidly. Neurogenesis Once a person reaches maturity, their neurons, the cells that make up the brain and nervous system, stop dividing. Neurons are long-lived, so this is usually not a problem. However, damage to nerve cells does not heal and can leave a person paralyzed for life, such as actor Christopher Reeves. Research into neurogenesis, the process of coaxing neurons to divide again, could find a cure to restore those with nervous system injuries to full health. Synthetic Neurotransmitters Neurotransmitters are the chemicals by which the cells of the brain and nervous system communicate with each other. They are the chemicals that we use to think, to feel and to control our own bodies. Many diseases, such as Parkinson’s, appear to be caused by a dysfunction of neurotransmitters. Creating our own synthetic neurotransmitters would allow the development of treatments for these diseases. David Eagleman does research in neurology and envisions a future where novel sensory inputs can be connected to the brain. Click here to lean more about David Eagleman’s research projects. Physics———————————- Everything in the universe is subject to the laws of physics, and biological organisms are no exception. Therefore, advances in our understanding of physics can be used to drive forward research into cures for diseases. Whether it is the electromagnetic forces that determine how drugs interact with cellular receptors, or the complex fluid dynamics that provide insight into cardiac health, the applications of physics towards biomedical research are numerous and profound. The Cure Is Now supports the advancement of physics in order to fuel progress in medicine. Regenerative Medicine—————————————— The body has an excellent capacity for self-renewal, but there are limits to its powers. Although lost skin can be regrown, a lost limb or organ cannot. If a person’s nervous system is damaged and they are paralyzed, there is no way to repair that damage. Furthermore, the ability of the body to regenerate itself decrease with age, leaving the elderly prone to death or suffering from stresses that would barely harm a younger person. Regenerative medicine focuses on repairing damage to the body that cannot be repaired by other means; stem cells are integral to this strategy, as their ability to be programmed into any type of cell makes them the ideal tool for rebuilding biological structures. Successful research into regenerative medicine would mean that there would be almost no type of injury that could not be repaired. John Schloendorn is the CEO of ImmunePath, which is involved in developing stem cell therapies for cancer and radiation injuries. Click here to lean more about John Schloendorn’s research projects.  

    thecureisnow 10 months ago respond

  • Our Plan:

    Our Plan: The Cure Is Now has carefully crafted a plan with short, medium & long term goals. The Cure Is Now breaks its mission into 3 primary programs respectively, which include: Awareness campaigns Education initiatives Scientific research The first two, Awareness Campaigns and Education Initiatives are designed to inform and energize the public. Imagine the same level of excitement that America embraced in the moon race during the space age, where on a mass scale the nation actively supported president Kennedy’s initiative to put a man on the moon. We believe that if our citizens were aware of how much larger an achievement The Singularity is, they would be inspired. More significant than even the creation of the Internet, the public would happily embrace the wonders that this technology will bring to society. What our society needs is a “Manhattan Project” scale national imperative. The Cure Is Now Awareness Campaigns and Education Initiatives will slowly but surely show the public that these illusive cures for these miserable diseases will indeed be possible. Through the technologies and their medical applications, The Cure Is Now is fostering, encouraging and developing these treatments. The second large scale phase of our plan is scientific research. Once the public is aware of why funding for this type of research is a national priority, we would like to help aid in the structuring scientific research and the construction of the worlds most advanced research facility which will serve as an international example for many like research facilities to be built around the globe. In order for the general public to understand how the root level approach, utilizing emerging and advanced technologies can find cures they must be made aware of this possibility int he first place, and then must be educated on its details. the cure is now plans to utilize large scale, multi facited marketing, advertising and other forms of media to spread this information as widely as possible. the objective is to generate as much cooperation and funding as possible to further scientific research, and the construction of a world class research facility, and ultimately several research facilities throughout the world.  

    thecureisnow 10 months ago respond

  • Diseases And Technologies:

    Diseases and Technologies: The Cure Is Now is a science & technology advocacy and research organization. Applying new technology to a variety of medical problems is our goal. One of our many programs is to develop, adapt and converge disparate and emerging technologies in brilliant and innovative ways that result in breakthrough medical solutions. We are not so bold as to think that we can solely tackle all of the diseases in the world, when thousands of such organizations have failed to do so collectively - it is precisely the opposite. We are the only medical research & advocacy organization with specific programs that are developing the technologies that other organizations will be able to utilize to achieve their individual missions. Just like small pox and polio were eradicated because of technological advancements, other diseases will eventually be eliminated too. Breakthrough technological opportunities are just now unfolding before us, and the next several years ahead will be the fulcrum where a fundamental paradigm-shift occurs and The Cure is Now will take advantage of this. This website offers clear, detailed and unambiguous information, including specifics on our plan and the details of programs that will be utilized to achieve the goal in our mission statement: the elimination of disease through technology. We Need The Cures, The Time Is Now, The Cure Is Now! Here is a partial list of emerging and advancing technologies that we believe, when combined and matured, are critical: Aging Research Artificial Intelligence Biocomputing Biotechnology Brain Mapping Brain-Computer Interfaces Cognitive Enhancement Cognitive Technology Complex Systems Simulations Cybernetic Systems Cytopathology Genetics Human-Machine Interfaces Humanoid Robotics Information Technology Manageable Matter Material Science Nano-Robotics Nanotechnology Neuron Level Connectivity Neuroscience Organ Manufacturing Personalized Immunotherapy Physics Regenerative Medicine Robotics Alzheimer’s Disease: Alzheimer’s: Alzheimer’s is a form of dementia; it is a progressive disease that often results in memory loss and other mental functions. The connection between brain cells deteriorates and eventually dies. It is believed that the onset of Alzheimer’s is due to a combination of genetics, lifestyle and environmental factors. Symptoms of Alzheimer’s include: forgetfulness, confusion, memory loss; in particular short-term memory loss, difficulty remembering thoughts and organizing thoughts amongst other symptoms. Unfortunately, there is no cure for this disease. Alzheimer’s is the 6th leading cause of death in the United States. There are more than 5 million Americans living with the disease. 1 in 3 senior citizens die with this disease. It is expected to cost the nation $203 billion in 2013 alone, the number is only rising with an estimate cost of $1.2 trillion by 2050. This is why it is imperative that we find a cure for this disease. Cancer: Cancers starts as a result of abnormal cells growing out of control. Our bodies are made up of trillions of living cells. The normal body cells grow, divide and die in systematic time. Cancer occurs when cells in the body start to grow out of control. Instead of the cells dying, cancer cells continue to grow and form new and abnormal cells. The cells invade other tissue thus causing cancer cells. Cancer cells can develop as a result of DNA (deoxyribonucleic acid) reasons or environmental issues. Environmental factors are commonly cigarette smoking or sun exposure. There are more than 100 types of cancers; breast cancer, skin cancer lung cancer, colon cancer, prostate cancer, leukemia to name a few. In most cases there are signs and symptoms that you have cancer. Sometimes these symptoms are too late however; the commonly known signs are; fever, fast breathing, weight loss, fatigue, abnormal lung sound, pneumonia, weakness aching, shortness of breath amongst many others. As cancer grows it begins to push on nearby organs, blood vessels and nerves. For a lot of these cancers early detection is imperative because once it has reach a critical stage there is little or no cure for most of these diseases. About 1,660,290 new cases of cancer will to be diagnosed in 2013 alone. It is projected that roughly 580,350 Americans will die of cancer that is almost 1,600 people a day. Cancer is the second most common cause of death in the United States, accounting for almost 1 in 4 deaths. 2 in every 3 people are diagnosed with cancer today. Cardiovascular: Cardiovascular disease also known as heart disease refers to conditions that involves narrowed or blocked blood vessels that prevent your heart, brain or other parts of your body from receiving sufficient blood. These include coronary artery disease, heart rhythm problems, heart infections and heart defects. The most common type of heart disease is coronary artery disease (CAD); this often leads to heart attacks. Cardiovascular disease symptoms include chest pain, shortness of breath and pain, numbness, weakness or coldness in your legs or arms, if the blood vessels are narrowed in your body. Arteries are blood vessels that carry oxygen and nutrients from your heart to the rest of your body, overtime too much pressure in your arteries can make the walls thick and stiff restricting blood flow to your organs. Cardiovascular problem is commonly caused by unhealthy diets, lack of exercise, being overweight and smoking. 600,000 people die of heart disease in the United States every year that is, 1 in every 4 deaths. Cardiovascular disease is the leading cause of death for both men and women. This disease alone costs United States $108.9 billion each year. Cell and Tissue Transplant: Human cells or tissue intended for implantation, transplantation, infusion ortransfer into a human recipient. Such transplant that can be done are bone, skin, corneas, ligament, tendons, dura mater, heart valve, hematopoietic stem/progenitor cells, oocytes and semen. In recent years tissue and cell transplantation has inevitably seen a huge demand. Transplantation of this material has been able to save ones life. We currently have a shortage of cell and tissue; with the help of donors we are able to save peoples lives. Cerebrovascular Disease: Cerebrovascular Disease is a condition developed due to complications with the blood vessels that supply blood to the brain. There are a number of Cerebrovascular diseases: stroke, transient ischaemic attack (TIA), subarachnoid hemorrhage and vascular dementia. Stroke is where the blood supply to the brain is obstructed. Transient Ischaemic Attack (TIA) is a lack of blood supply – lack of oxygen to the brain. Subarachnoid Hemorrhage is where blood leaks out of the brain’s blood vessels. Vascular Dementia is where there are complications with blood circulations – brain not receiving enough blood and oxygen. Symptoms of these diseases are: persons face has gone to one side (unable to smile or mouth and eyes are lop sided), unable to raise their arms due to numbness and weakness, slurred speech, high temperature (fever) and seizures. Stroke is one of the leading causes of death in the United States. Of the 700,000 people affected, 500,000 of these are first attacks and 200,00 and reoccurring. Approximately 129,500 people die of Stroke each year. Chronic Obstructive Pulmonary Disease (COPD): Chronic Obstructive Pulmonary Disease also known as COPD is a progressive lung disease that makes it difficult to breath. The 2 most common conditions are: emphysema and chronic bronchitis. Emphysema develops when the air sacs (alveoli) are damaged in the lings. Chronic bronchitis is an inflammation of the airways that carry air to your lungs. Signs of lung damage do no occur until there is substantial destruction done. Symptoms of the disease include: shortness of breath, wheezing, tightness of the chest, chronic coughing, blueness of the lips and fingernails, lack of energy and unintentional weight loss. It is estimated that approximately 15 million people are reported to having Chronic Obstructive Pulmonary Disease. According to surveys done it is reported that woman are more likely to have COPD with 6.7% as opposed to men with 5.2%. Roughly 36.4% of people reported having COPD were former smokers, 38.7% continued to smoke and 43.7% had a history of asthma. Cri-du-chat Syndrome: Cri-du-char Syndrome is a rare condition that is cause by a problem with chromosome 5. There is a break in chromosome 5, this generally occurs while the sperm or egg cell is developing. The syndrome’s name is based on the infant’s cry, which sounds like a high-pitched cat. People who gave Cri-du-chat Syndrome have very distinctive features; small head, an usually round face, small chin, wide set eyes, folds of skin over there eyes and a small bridge of the nose. As children grow with the condition they experience heart defects, muscular or skeletal problems, hearing or sight problems or pool muscle tone. There is a tendency to have difficulty walking and talking. There is no cure for this condition however; children can go through therapy to assist them with their language skills and motor skills. 80% of cases come from the father’s sperms as a result of the chromosome break. It affects 1 in 20,000 and 1 in 50,000 babies. Degenerative Disc Disease: Degenerative disc disease (DDD) is the slow deterioration of the discs that are between the vertebrae in the spine. The discs in the spine act as a shock absorber for our body weight. Overtime the discs wear out. Thus, this disease occurs in older people as part of the aging process. Symptoms include chronic lower back pain that go through to the hip, buttocks or thighs, sporadic tingling or weakness through the knees, hands and fingers. There is no cure for this disease however; putting ice or heat to the affect area and using anti-inflammatories can relive pain. Down Syndrome: Down Syndrome is a genetic disease that is developed as a result of an extra chromosome 21. At the time of conception, the fetus inherits genetics from parents, 23 from the father and 23 from the mother a total of 46 chromosomes. In Down syndrome cases, the fetus gets an additional chromosome, chromosome 21, which results in a total of 47 chromosomes instead of the usual 46. The disease causes delays in the developments and physical features. Common traits of Down syndrome are low muscle tone, small stature, and upward slant to the eyes just to name a few. Down syndrome is the most common genetic condition with 1 in every 691 babies in the United States born with the disease. There are roughly 400,000 people in the United States that have Down syndrome and 6,000 babies born with Down syndrome every year in the United States alone. Dyskeratosis Congenita: Dyskeratosis Congenita is a bone marrow disorder; it is generally a genetic disease that is inherited. People who have this condition experience failure of bone marrow – the bones does not make enough of the blood cells the body needs. People with Dyskeratosis Congenita tend to develop other life-threatening disease: Aplastic Anemia (occurs when bone marrow does not produce new blood cells), Myelodysplatic Syndrome and Leukemia (immature blood cells fail to develop normally – also know as Leukemia). There are 3 main symptoms that help diagnose the disorder: a reddish, wart type rash on the face, neck and chest, white patches in the mouth and fingernails and toenails are not shaped normally. There is no cure for the disease however, there is the option of bone marrow transplant, which could help with a longer lifespan. The statistics on such a disease are not known it is estimated that Dyskeratosis Congenita affected 1 in million people. Fanconi Anemia: Fanconi Anemia is a genetic blood disorder that eventually results in bone marrow failure. The disease prevents your bone marrow from producing enough new blood cells for your body to work normally. The condition causes bone marrow to make damaged blood cells, which could lead to other serious health issues like Leukemia and blood cancer. As the name suggests Fanconi Anemia is a type of Anemia, more particularly Aplastic Anemia. Anemia refers to condition where the red blood cell count is considerably lower than normal. Aplastic Anemic is where the bone marrow stops making the three types of blood cells: white blood cells, red blood cells and platelets. Low white blood cells your body has difficulty fighting infectious disease, low red blood cells the body tissue does not get enough oxygen and with platelets your blood cannot clot normally. Any deficiencies can cause serious bleeding problems. Symptoms of the condition include: fatigue, dizziness, headaches, pale skin, chest pain, bleed and bruise easy, tiny red or purple spots on the skin, bone defects and poor appetite. 95% of people who develop Fanconi Anemia are a result of genetic complications. The average lifespan for a person living with Fanconi Anemia is roughly 29 years old. General Immunity: The immune system is made up of cells, proteins, tissues and organs that work respectively together to protect the body. It helps to defend the human body against infectious germs and microorganisms. The cells that protect the body are white blood cells or leukocytes. There are 2 sub-sections of leukocytes: phagocytes and lymphocytes. Phagocytes cells remove invading organisms. There are different cells that are considered phagocytes, the most common being neutrophil. Neutrophil’s primary concern is to fight bacteria. Lymphocytes cells act as a remembering cell; they recognize previous invading organisms and destroy them. There are 2 types of lymphocytes cells: B-lymphocytes and T lymphocytes. B-lymphocytes search for the invading organisms whereas; T lymphocytes eliminate the invading organism. There are issues that occur when the immune system is not working correctly, the primary Immunodeficiency disorders are: IgA deficiency, severe combined immunodeficiency (SCID), DiGeorge syndrome (thymic dyslasia) and Chediak-Higashi syndrome and chronic granulomatous. IgA deficiency is the mosy common form, it is a immunoglobulin that is found mostly in saliva. This disorder cannot produce enough antibody thus people have allergies, more colds. Severe combined immunodeficiency (SCID) is a serious immune system disease where there is a lack of both B and T lymphocytes making it virtually impossible to fight off infectious diseases. DiGeorge Syndrome (thymic dyslasia) is a birth defect where a child is born without a thymus gland. Chediak-Higashi syndrome and chronic granulomatous is the inability of neutrophil to function normally. There are also secondary immunodeficiency’s these are: HIV/Aids and immunodeficiency’s caused by medication. HIV/AIDS: HIV also known as Human Immunodeficiency Virus is one of the deadliest disease in human history. HIV breaks down the immune system that protects our bodies against disease. AIDS is Acquired Immune Deficiency Syndrome. It’s the most advance stage of HIV. HIV eliminates a defense cell in the body called CD4 helper lymphocyte. The lymphocytes are part of the bodies’ immune system, the fight infections in out body. As a result of HIV the immune system becomes weak and people get serious infection they otherwise would not have got. HIV is transmitted from an infected person through blood, semen, vaginal fluids and breast milk. Approximately 40,000 women and men get HIV each year in the United States. There is no cure for HIV/AIDS however, there are treatments for people living with this disease. HIV/AIDS is affected hugely in Africa with roughly 33.4 million people living with HIV, 2.7 million new infections of HIV and 2 million deaths from AIDS. Idiopathic Pulmonary Fibrosis: The cause for Idiopathic Pulmonary Fibrosis is currently unknown. It is damaging or the scarring of the lungs tissue. The scarring of the tissue in the lungs and between the air sac (alveoli) makes it difficult for oxygen to pass through to the bloodstream. It is believed that the condition is due to an inflammatory response to an unknown substance or injury. It is suggested that people who work around dust or fumes (farmers, hairdressers, metal workers) have a higher risk of developing the condition. Symptoms include: chest pain, coughing, shortness of breath, fatigue and weight loss. The inability of the lungs to deliver oxygen could cause heart attack, respiratory failure, stroke, blood clots in the lung, lung infection or lung cancer. Idiopathic Pulmonary Fibrosis affected 128,100 people in America with roughly 48,000 new cases every year. Approximately 40,00 people die each year as a result of the condition. Liver Cirrhosis: The liver is the largest solid organ in the body. It plays a vital role in our bodies. Some of the essential function it has is: manufacturing blood proteins that aid against clotting, it helps transport oxygen, it stores excess nutrients and returns nutrients to the bloodstream, it removes harmful substances in the bloodstream such as drugs and breaks down saturated fats. Liver Cirrhosis develops when the healthy liver tissue is replaced with the scar tissue, inevitably preventing the liver from functioning correctly. The cause of Liver Cirrhosis is alcohol abuse, fatty liver and Hepatitis C as well as other causes. Fatigue and loss of energy, poor appetite, weight lose, nausea or belly pain, easy bruising and abnormal bleeding are some symptoms of Liver Cirrhosis. Liver Cirrhosis is currently incurable with 31,000 people in the United States dying each year as a result of the disease. Macular Degeneration: Macular Degeneration is a chronic disease that results in central vision loss. This disease eradicates your sharp and central vision, the ability to see fine detail. The cause for this disease is unknown however it has a decency to affect people later in ages. There are 2 types of macular degeneration: wet and dry. Wet Macular degeneration happens when abnormal blood vessels grow under the macula and leak fluid or blood. Dry Macula Denegation occurs when light sensitive cells break down in the macula. Symptoms include visual distortion, decline in central vision, blurry spots in field of vision, need for bright light when reading, difficulty recognizing faces, hallucinations of shapes or people. Macular Degeneration is the leading cause of blindness in adults aged 60 and older. 200,000 are diagnosed with Macular Degeneration every year in the United States. Muscular Dystrophy: Muscular Dystrophy is a group of genetic diseases, where the genes are missing information, which prevent them from making proteins needed for healthy muscles. This inherited disease weakens the muscle fibers making them more susceptible to damage. The disease overtime weakens the muscles so much so that people lose their ability to walk or sit up, in some cases shorten a person’s lifespan. This condition commonly occurs in boys with signs of Muscular Dystrophy at birth. Signs and symptoms may be detected at youth such as; frequent falling, difficulty getting up, trouble running or jumping and learning disabilities. The onset of Muscular Dystrophy starts between 3-5, the disease progresses rather rapidly. By the time the child is 12 they are unable to walk. It is estimated that 1 in every 3,500 to 5,000 boys are born with this condition, 400-600 new cases every year in America. Osteoarthritis: Osteoarthritis is a form of arthritis; it is the most common form. The chronic disease occurs when the protective cartilage on the end of your bones to break down. The wear down of your bones causes the bones to run against each other, this eventually causes stiffness, pain and loss of movement in the joint. Risk factors for osteoarthritis include being overweight or obese, aging, injured joints, genetics and muscle weakness. Symptoms of osteoarthritis are pain in the joints of after movement, tenderness in your joints, stiffness after a period of inactivity or loss of flexibility. There are treatment options such as: improving daily activity, exercise, weight control, therapy and medications however, there is nothing that can eliminate the disease in its entirety once you have been diagnosed with it. It is said that an estimate 27 million people in the United States live with Osteoarthritis. Osteoporosis: The causation of the bones to become thin, weak and fragile is known as Osteoporosis. Bones are considered a living tissue, these living tissues are constantly being absorbed and replaced. Osteoporosis The condition develops when new bones do not remove old bones. This is a serious condition as a simple fall or mild stress like bending over could cause fractures or broken bones. Osteoporosis commonly occurs in the hips, wrist or spine. There are no such symptoms for osteoporosis until you have fractured or broken a bone. Risk factors are: aging, low body weight, taking certain medication, menopause and smoking. There is no cure for the condition however there ate treatments and prevention precaution’s you can take. You can eat a diet rich in calcium and vitamin D, exercise and do not smoke. Osteoporosis affects men and woman of all races however, there is a higher risk of white and Asian woman going through menopause. Approximately 9 million Americans currently have Osteoporosis. Roughly 60% of adults aged 50 and older are at risk of breaking bones. It is suggested that 1 in 2 woman and 1 in 4 men aged 50 and older will break bones due to Osteoporosis. Progeria: Progeria is a genetic disorder that causes rapid growth in a child’s age at the beginning of their first 2 years of life. It resembles normal human aging however it occurs in young children. At 12 months symptoms are visual such as: slow growth, hair loss, narrow or wrinkled face, baldness, short stature, large head, small jaw, dry and scaly skin, delay in teeth growth or completely obsolete. The average life expectancy for a child with Progeria is 13. They eventually die of heart problems or stroke. There is no cure for this disease. To date there is 103 known cases of children with Progeria. Rheumatoid Arthritis: Rheumatoid Arthritis is a disorder that is affects the small joints in your hands and feet. The chronic disease causes pain, stiffness, swelling and loss of function in the joints. The cause of Rheumatoid Arthritis is currently unknown; it is believed to be a result of environmental and genetic factors. For whatever reasons the immune system, which regularly protects the body, starts to attack the bodies own tissue specially the synovium and a thin membrane that lines the joints. Rheumatoid Arthritis is more common in women than in men, it generally occurs between the ages of 40 and 60. Approximately 1.3 million people in the United States have this disease; this is almost 1% of the nation’s adult population. Skin Aging: Everyone is aware that over time our skin ages, the most visual signs of aging are wrinkles, aging spots, dryness and sagging skin. Changes in skin age related to numerous factors; environment, genetics make-up, nutrition, aging and various other factors. Heat exposure is a common reason for this change in skin. More than 90% of all elderly people have some kind of skin disorder. Skin disorders can be caused by many conditions: diabetes, heart disease liver disease obesity, stress, climate, and loss of elasticity amongst many others. There is no cure for skin ageing however, there are precautionary steps one can take to slow down the aging process; prevent sunburnt, use sunscreen when outdoors, wear protective clothes and hats when in the sun. Tuberous Sclerosis: Tuberous Sclerosis is a rare genetic disease that causes benign tumors to grow in the brain and other areas like the kidney, heart, eyes, lungs and skin. This disease is a result of alterations in the TSC1 or TSC2 gene. The TSC1 and TSC2 genes stop cells from growing at a rapid pace or uncontrollably. Tuberous Sclerosis causes the cells to divide in a large manner, which leads to excessive lesions through the body. Symptoms include: seizures, developmental issues, behavioral problems, skin abnormalities, lung and kidney disease. There is no cure for the disease and no known factors for developing the disease other than genetics. Should parents have the disease themselves, there is a 50% chance the child may inherit the disease. Werner Syndrome: Werner Syndrome is a genetic condition associated with premature aging. Children who have this disorder will typically grow normally until they reach puberty. Youth with Werner Syndrome do not experience growth spurts. Generally, every cell has 2 genes one from the mother and the other from the father. People with the condition have a mutation in genes from both the mother and father. Once Werner Syndrome patient’s reach there twenties they commence getting gray hairs and loss of hair, a hoarse voice, and thin and hard skin. Symptoms of the disease are cataracts in eyes, skin changes (aging, tight skin, pigment changes and skin ulcers), wrinkles and loss of muscle tone, short stature and early graying of the hair. It is estimated that 1 in 200,000 people in the United States have Werner Syndrome. The condition is more common in places like Japan, where there is an estimated 30,000 living with the condition.  

    thecureisnow 10 months ago respond

  • Research Programs:

    Research Programs: The Cure is Now is ultimately committed to supporting groundbreaking research. Although the Awareness Campaigns and Education Initiatives are important, actual research is what lies at the heart of The Cure is Now. We are committed to bring life-saving cures to the public through the development of emerging and advanced technologies that are applied to medical treatments. The Cure is Now will support research via a three-step process: Phase 1 – Begin funding independent research and establishing a research, leadership & coordination center. Phase 2 – Build and staff small research cells. There will be four to start with: one in New York because it is poised to become a biotechnological hub, and is one of the financial centers of the world, one in Cambridge, MA because it is an academic center, one in Silicon Valley because it is a technology sector incubator, and an Advanced Research Facility, which will operate overseas specifically so that it can legally, morally & ethically operate outside of draconian political agendas and other practical restrictions, while respecting human rights and human life. Locations would include Africa and/or the Caribbean for clinical trials. Additionally Eastern Europe has demonstrated itself as a cost effective place to conduct research with well-educated, qualified and capable scientists that would offer significant and substantial savings while maintaining the high quality of research results and data capture. Phase 3 – Build, staff and manage a world-class research facility in New York City, firstly because New York is a strategically beneficial location and secondly because of the continued initiatives to establish New York as a biotechnological hub with advantages that only New York City can offer. Ancillary facilities that are not required to be at a central city hub will be located in less expensive areas. Guided by our research methodology, our lead scientists will work toward novel treatments and medicines to help us live longer, healthy lives.  

    thecureisnow 10 months ago respond

  • Education Initiatives:

    Education Initiatives: The Cure Is Now would like to educate the public on our mission and programs. There are many ways this can be accomplished. We feel one of the best ways for the public to really appreciate the severity of the challenge we face is to keep them properly informed. Knowledge is power. We know and understand that not everybody visiting our website and becoming part of the organization’s movement is going to have a technical, scientific, or medical background. But what the general public can understand, the general public can support. That is why it is important to emphasize why we stand out, and why you should contribute. Through extensive research, we have learned from scientists and doctors alike, many a valuable insight into emerging advanced technologies, specifically: nano/bio/information technologies, and combined cognitive sciences technology. In addition to the conventional, mainstream research methods, we also understand the importance of stem cell research, gene therapy, and most importantly, unknown and emerging methods, which will become the cornerstones of our success. Our scientists are aware that we need to invent procedures and systems to perform the techniques that aren’t even tangible yet, given today’s technological limitations. For example, doctors know how to create a machine interface that links two ends of a person’s severed spinal cord, so that the person won’t be paralyzed anymore. The device and technology to make that happen doesn’t exist yet, and the importance of funding these ideas is paramount. Inventions will beget inventions. This is only the beginning of our potential. Because not everyone has been affected personally by a devastating disease, education on these matters is vital. If you share in a story that brings you face-to-face with the human element, the emotions, the joy of life, the pain of suffering, and the specter of facing death, you appreciate the scenario in an entirely different way. Imagine the power of a population truly inspired - but how to create that momentum? A great way to educate is through the art of film. We want to make educational movies that will expose diseases and explain them. This is an informative way to educate the public at large, and the profits from it would be reinvested into research. One day it will be possible to eliminate all disease from the earth, and we have decided to undertake a revolutionary new approach to curing disease by attacking at its “root level” - a way that is not being done yet. In many cases, symptoms are masked, but the underlying root causes of the disorder pervade & persist. We are helping shape and pioneer the technologies that are not yet in existence, to come up with cures that also do not exist – yet. There are several diseases that The Cure Is Now research will simultaneously benefit. Only time will tell how many and how fast they will arrive. The more funding we have for scientists, equipment, overhead and materials, the better our odds are. Please Donate now.  

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  • Awareness Campaigns:

    Awareness Campaigns: The Cure Is Now is dedicated to raising awareness about the opportunity that we as a human society have in regards to science and technology. Breakthroughs in stem cell research, nanotechnology, biochemistry, genetics, neurology and bio engineering often go unnoticed by the public at large. The Cure is Now is dedicated to raising awareness about these discoveries and applications to the general public. The Cure Is Now utilizes several approaches for community outreach including: “We Are The Cure” benefit album, films, videos, print material, webpages, social networking and our Community Outreach Vehicle (COV).  

    thecureisnow 10 months ago respond

  • Programs Summary:

    Programs Summary: The Cure Is Now plans on achieving its Mission through several Programs & Operations. We are utilizing a phased approach where operations are conducted in their most efficient order. The following is a list of some, but not all of our Programs and Operations: —Our three core programs include: Awareness Campaigns Education Initiatives Research Facility —Ancillary Programs include: Community Outreach Vehicle Advocacy Applied Research Pediatric Research Awareness Campaigns: The Cure Is Now plans to spread awareness and education through various methods, including an interactive, easy to navigate website. Here you can learn all about The Cure Is Now, including what we stand for, where donations go, how to advocate or volunteer, upcoming events, and how to make a charitable donation. We also utilize a mobile Community Outreach Vehicle to travel to various places in America to help spread our messages directly through audio / visual content that is stimulating and aesthetically relevant. Our advertising and marketing programs are bold and unique, designed to target people who might not otherwise interact with traditional media. We have new radio and TV commercials that we will broadcast nationally, to reach a wide population. We also are creating a music album with an eclectic group of artists dedicated to getting our message out to as many individuals as possible. The album is entitled: “We Are the Cure.” We believe that music is a great marketing medium, and are honored that these artists dedicated their time and love for music to come together and help us reach out. The Cure Is Now Outreach Program was established to spread information to the public about our diverse awareness projects and initiatives. The Cure Is Now utilizes several approaches for community outreach including: multimedia, films and videos, print material, web-pages, social networking, and our Community Outreach Vehicle (COV). Education Initiatives: The Cure Is Now would like to educate the public on our mission and programs. There are many ways this can be accomplished. We feel one of the best ways for the public to really appreciate the severity of the challenge we face is to keep them properly informed. Knowledge is power. We know and understand that not everybody visiting our website and becoming part of the organization’s movement is going to have a technical, scientific, or medical background. However, what the public can understand, the general public can support. That is why it is important to emphasize why we stand out, and why individuals should contribute. Through extensive research, we have learned from scientists and doctors alike, many a valuable insight into emerging advanced technologies, specifically: nano/bio/information technologies, and combined cognitive sciences technology. In addition to the conventional, mainstream research methods, we also understand the importance of stem cell research, gene therapy, and most importantly, unknown and emerging methods, which will become the cornerstones of our success. Our scientists are aware that we need to invent procedures and systems to perform the techniques that aren’t even tangible yet, given today’s technological limitations. For example, doctors recognize the need to create a machine interface that links two ends of a person’s severed spinal cord, so that the person won’t be paralyzed anymore. The device and technology to make that happen doesn’t exist yet, and the importance of funding these ideas is paramount. Inventions will beget inventions. This is only the beginning of our potential. Fortunately, a devastating disease will not personally affect everyone; and education on these matters is vital. If you share in somebody’s personal story, which brings you face-to-face with the human element, their emotions, the joy of life, as well as their pain & suffering, and the specter of facing death, you appreciate the scenario in more personal & evocative way than by just reading some statistic. Imagine the power of a population truly inspired - but how do you create that momentum? A great way to educate is through the art of film. We want to make educational movies that will expose diseases and explain the root level approach to a cure. This is an informative way to educate the public at large, and the profits from it would be reinvested into research. Research Facility: The Cure Is Now is already planning to fund one of the world’s most advanced research facilities dedicated to eliminating disease as a cause of human suffering and death. We aim to use advanced technological approaches to solving age-old problems through creative thinking, unconventional approaches, in addition to conventional medicine and general science. This will yield the answers for which we have been searching. Think of it in these terms: 500 people working full time in every imaginable discipline, with projects running 24 hours a day, 7 days a week. There are advantages to doing it this way: By having a closely-knit team led by some of the brightest minds in the world, things happen fast. We want to give these brilliant people of today and tomorrow the tools they need to succeed. Our building’s floor plan includes several laboratories. Why is this needed? Running experiments efficiently: if we have to wait a long time to get results back from other labs, it takes longer to make progress. Giving scientists the control they need for accuracy, and making the process less time consuming. Many of the tests are long term and need to be run 24 hours per day, seven days a week. (For example: separating proteins & enzymes, etc…). Community Outreach Vehicle: One of our main Awareness Campaigns is going to be our Community Outreach Vehicle. The purpose of it is to bring our message to people in their communities and to disseminate information using non-traditional methods. This mobile office allows us to expand our efforts on a regional, and then national level, and gives our members more access to our staff in the field, by bringing someone directly to you. The vehicle is equipped with space for marketing representatives, where we can hold private and comfortable information sessions. Check back to our website to find out when our COV will be in your area! The vehicle has been maximized for multi-use applications. We find this a very efficient use of our resources because we are not limited to one geographic area. Rather than investing in several offices, and diverting our program budgets into offices all over the country, we achieve the same results with our COV. This way, we bring ourselves to the communities, rather than waiting for people to seek us out. Our Community Outreach Vehicle will be staffed by one of our outreach specialists. This project is an effort to make our information available to individuals who would otherwise have difficulty visiting our New York-based Center. The center will be used to provide direct interaction with our members, potential donors, researchers, scientists, doctors, power brokers and other individuals. Help us spread the word. Advocacy: It is our civic responsibility to ensure that elected officials make it a priority to ensure that everything that can legally be done to help fund research is explored. Ultimately, getting dollars to research facilities, doctors, scientists, and skilled technicians is the goal. They need specific tools, some that haven’t even been invented yet, to get their work done. Disease is a political, medical, social, and economic issue in today’s society. Life and death decisions about disease are made every day, not just in doctor’s offices, but also in Congress and Senate alike. We want lawmakers and lobbyists nationwide to hear loud and clear that curing disease is a top priority of the American people. Applied Research: Applied Research is key. We aim to conduct various research operations, based in the New York Metropolitan area as well as nationally. We are currently working with architects, developers, scientists and researchers to create the world’s most advanced research and development center possible. It will be fully equipped and function as a central hub for some of the world’s brightest minds. This means we will have the best equipment, laboratories, tools, and the most talented people working on scientific projects. There are a number of professionals who are able to help our entity create a working model for applied research. We want to fund scientists and researchers with donations and support by providing them with access to a dedicated laboratory and the various technological needs and equipment to conduct their experiments. Many other research organizations are wasting energy and money, but we are developing specialized software that will help eliminate wasted efforts and bring us closer to discoveries. These new techniques are at the core of our research – and are encapsulated in our “Root Level Approach” to research & development. One day it will be possible to eliminate all disease from the earth, and we have decided to undertake a revolutionary new approach to curing disease by attacking at its “root level” - a way that is not being done yet. In many cases, symptoms are masked, but the underlying root causes of the disorder to pervade & persist. We are helping shape and pioneer the technologies that are not yet in existence, to come up with cures that also do not exist – yet. There are several diseases that The Cure is Now research will simultaneously benefit. Only time will tell how many and how fast they will arrive. The more funding we have for scientists, equipment, overhead and materials, the better our odds are. Pediatric Research: The Cure is Now Pediatric Research division places a specific emphasis on directing resources and efforts towards the youngest, most innocent, and most vulnerable victims: pediatric patients. Being told you have, for example: cancer; are three words that no one wants to hear. How do you tell that to an innocent child, who has yet to live their life? The Cure Is Now is here to help you, and to help make a difference to others. Getting involved with our program is vital, and spreading awareness and education is the first step. Our organization has several programs in place, so that everyone and anyone can get involved and start making a difference. We want to help end misinformation and ignorance. There are many ways to get involved in advancing our Pediatric Research programs. You can volunteer at our organization, you can share your story on our website, you can share our website with your friends and family, you can create an event or participate in one of our own, or you can make a donation. Most people are in the dark about the facts of what causes cancer, which cancers have a high survivability rate, and what technologies hold the key to eradicating cancer, especially pediatric cancer. The Cure Is Now is specifically creating awareness campaigns to inform people of the facts about cancer and its devastating impacts. Scientists and researchers are using cutting edge technologies to find cures. There is a vast array of technologies at our fingertips, and we are more knowledgeable about medicine now more than ever, but still only at the beginning of our potential.  

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  • Proposed Research Facility:

    Proposed Research Facility: The Cure Is Now is already planning to fund one of the world’s most advanced research facilities dedicated to eliminating disease as a cause of human suffering and death. We aim to use advanced technological approaches to solving age-old problems through creative thinking, unconventional approaches, in addition to conventional medicine and general science. This will yield the answers for which we have been searching. Think of it in these terms: 500 people working full time in every imaginable discipline, with projects running 24 hours a day, 7 days a week. There are advantages to doing it this way: By having a closely knit team led by some of the brightest minds in the world, things happen fast. We want to give the brilliant minds of today and tomorrow the tools they need to succeed. Our floor plan includes several laboratories. Why is this needed? —Running experiments efficiently: if we have to wait a long time to get results back from other labs, it takes longer to make progress. —Giving scientists the control they need for accuracy, and making the process less time consuming. —Many of the tests are long term and need to be run 24 hours per day, seven days a week. (For example: separating proteins & enzymes, etc…). —The practical real time of exchange of information between experiments. For more information on some of the laboratory equipment that is needed, please check out our Laboratory and Scientific Equipment Proposed Budget. If you would like to donate specific items to our facility, including computers, microscopes, lab equipment, please contact: donate@thecureisnow.org.  

    thecureisnow 10 months ago respond

  • In-Kind Donations:

    In-Kind Donations: Donations of goods and services are extremely valuable to The Cure Is Now. This type of charitable donation can be made by individuals or organizations and ranges anywhere from an automobile to office equipment, printer paper, silent auction items, office spaces, or consulting services. Although they are often welcome assets, grantees must be sure to document them properly. The Cure Is Now depends on generous donations from private citizens and businesses to continue it’s operations. Not all the contributions that keep our organizations running, however, are cash. “In-kind giving” refers to contributions of goods and services that are of value to our nonprofit organization. Businesses do it, corporations do it, and so do individual donors. Some potential items and services that can be donated are: Vehicles: If you are thinking of donating a used car or other vehicle, please visit the donate your vehicle section. There is no cost to you and you don’t have to live in New York City. When you donate a car, truck, boat, RV or other vehicle to The Cure Is Now vehicle donation program, you are helping our organization fulfill it’s goals through it’s various programs. Your vehicle donation will help us find the cures, and give hope. The Cure Is Now Car donation process is quick, easy and efficient. Call the The Cure Is Now toll free number 1-877-870-CURE (2873) or process your vehicle donation online today! Simply donate on-line by printing the forms at the end of the donation wizard, submit the forms with your vehicle’s title and we will call you to coordinate the pick up of your vehicle. Office Equipment: The Cure Is Now greatly needs office equipment. Because of the temperamental nature of some office equipment, we only accept new factory sealed office equipment. (We have found that fixing an old photocopier, for example, is often more expensive than just buying a new one.) Services: We welcome offers of pro-bono services in many areas, including design, construction, legal assistance for printing, mailing, and photography. If you would like to volunteer, please click here. Building Materials: The Cure Is Now only accepts building materials approved by our construction department. Please donate new construction materials in quantity so that we can build our research facility. For information about donating construction equipment and materials, please email: donate@thecureisnow.org. Please email details of your suggested donation to: donate@thecureisnow.org. Tools: We need hand tools in new condition, such as tape measures, screwdrivers, and hammers. Larger items, such as saws or tile cutters, etc.. are always welcome. Furniture: We do not have the staff or facilities available for furniture or appliance pick-ups. Please contact other charitable organizations with your offers. Other items & services: If there are any other items that you would like to donate, and would like to know if they are of any use to our organization, please email us at: donate@thecureisnow.org Please place an accurate value on your donation. Please make sure that you keep a record of what you give. Document everything with photographs if possible. Let our organization know the value of the in-kind donation, as we will need that information for grants, etc., as we must specify if we receive in-kind donations, and the value of these in-kind donations. Such record keeping is for your benefit as well as the charity’s, especially if you intend on writing off your donation. IRS Publication 561 explains how to determine the fair market value of your donation. If you’re thinking about donating a vehicle, keep an eye out for possible new legislation that may tighten valuation regulations. ***Please don’t always assume your donation is tax deductible: Not every in-kind donation is tax-deductible. Donated services, although often welcomed by organizations, generally cannot be written off. IRS Publication 526 outlines what types of donations can be deducted and how to claim a deduction.  

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  • Development:

    Development: Incorporated at the end of 2009, The Cure is Now is a national, nonprofit organization that has taken bold strides in the past few years. Since 2010, The Cure is Now has launched all three of its programs, began fundraising and is looking to expand its core and research staff. In summary, our mission is: To accelerate medical research To use a convergence of emerging technologies to combat diseases in groundbreaking and novel ways To cure diseases We need the cures. The time is now. The Cure is Now. Several fundraising programs have been put in place to help raise the necessary support to achieve our ambitious hopes and dreams. We rely on the generosity of individuals, foundations and corporations to help us manifest our important vision. The programs we run are the most critical and prioritized aspects of our nonprofit group. You can learn more about our programs here (link). For a detailed list of how we apply the funds we raise, please click here (link). Please consider supporting our mission through our diverse fundraising programs:  

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  • Executive Director-AnnMarie Santiago

    Executive Director-AnnMarie Santiago I was born in 1980 in a poor neighborhood in Queens, NY. I witnessed the effects of disease and poverty in my community, and was determined at a young age to do something about it. I went to Lehman College and graduated with a Bachelor’s in Business Administration. I was constantly involved with charity work that focused on giving back to communities. The direct inspiration that made me start The Cure Is Now was the passing of several people that were very close to me. It put life into perspective for me, and made me think about those suffering out there that aren’t fortunate enough to have proper medical care, prevention screenings, advocates, or a support system. What about those children left behind from dying parents? Or even parents outliving their children who die from child-prone Cancers? The answers to these questions have always left me feeling uneasy. I was determined to make a strong commitment to this organization and not go half-way on any matter. I really want to emphasize spreading awareness and education about disease and the importance of nano and bio technology. Through The Cure Is Now, I am focused on developing new advances, and to bring hope to communities around the world. I am looking for results and answers, which is why it is so important to donate to this cause. We are fortunate enough to live in a time with cutting edge technology, and we would be fools not to take advantage of that – we cannot fall short, and we cannot (and will not) fail. Funding is a necessary tool for every charity and I have been exploring traditional and non traditional methods to fundraising. This includes sponsored events, the aid of video marketing tools such as youtube, and the aid of online communities such as Facebook. This way, it makes philanthropy more relevant and easily accessible. Using my business expertise, I am aiming towards “killing two birds with one stone” with my program operations. The first is spreading awareness, particularly through social networking. The second, will be to research cures, primarily through a paradigm shift in thinking. This shift will fundamentally change the scientific community’s approach to thinking about problems at their root-level causes and how to leverage emerging technologies to tackle these problems in ways that weren’t technologically possible before. AnnMarie Santiago Executive Director The Cure Is Now  

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  • Chair, Science Board:

    Chair, Science Board: Dr. Aubrey de Grey: Chair, Science Advisory Board Dr. Aubrey de Grey is a biomedical gerontologist and in addition to being the Chair of the Science Advisory Board at The Cure is Now, is the Chief Science Officer of SENS Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging. He received his BA and Ph.D. from the University of Cambridge in 1985 and 2000 respectively. His original field was computer science, and he did research in the private sector for six years in the area of software verification before switching to biogerontology in the mid-1990s. His research interests encompass the characterization of all the accumulating and eventually pathogenic molecular and cellular side effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. He has developed a possibly comprehensive plan for such repair, termed Strategies for Engineered Negligible Senescence (SENS), which breaks aging down into seven major classes of damage and identifies detailed approaches to addressing each one. A key aspect of SENS is that it can potentially extend healthy lifespan without limit, even though these repair processes will probably never be perfect, as the repair only needs to approach perfection rapidly enough to keep the overall level of damage below pathogenic levels. Dr. de Grey has termed this required rate of improvement of repair therapies “longevity escape velocity”. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.  

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  • Chief Science Advisor:

    Chief Science Advisor: The Chief Science Advisor represents The Cure is Now to the scientific community. Helping The Cure is Now navigate scientific communities, technical language, and research opportunities, The Chief Science Advisor plays a critical role in the growth and development of The Cure is Now’s research programs. The Chief Science Advisor’s primary functions are to: Effectively represent The Cure is Now to the scientific community Advise The Cure is Now on critical, scientific decisions Cohere The Cure is Now’s scientific constituents, aggregate common ideas and support beneficial partnerships Deliver important science-related news and potential opportunities to The Cure is Now The Scientific Advisor and the Scientific Advisory Board (SAB) for The Cure is Now® (TCIN) provide strategic guidance and direction for the organization, with a particular focus on the research and scientific programs. In addition, the Advisor and Board play a key role in guiding and prioritizing TCIN’s global research initiative and investment. The SAB also serves as the executive committee of the TCIN researchers. The SAB is led by the Chief Scientific Advisor and will be comprised of leaders in various fields of research, clinical practice and advocacy who have made significant contributions in science and are committed to furthering the mission of the organization. The Cure is Now is a national non-profit organization whose mission is to provide awareness, help educate and accelerate the discovery and development of therapeutics for the prevention, treatment and potential cure of various diseases. The funds raised by TCIN will be used to help support research on radically advanced and emerging technologies that will result in the identification of potential target and therapeutics for diseases. Applications will be solicited from outstanding scientists, reviewed and the SAB will select meritorious applications to fund to help support the goals of the organization. In addition, the goal of TCIN is to raise funds to establish a world class research facility and to recruit exceptional researchers to help understand the mechanisms of disease and develop potential therapeutic approaches. Call-to-action The most effective way to help TCIN achieve its goals would be to provide a donation to the general research fund of the organization.  

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