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55 Iconic "Grey's Anatomy" Moments That Happened In The Last 10 Years

"He's very dreamy, but he is not the sun. You are."

🚨Obviously MASSIVE spoilers ahead, including from the most recent season!🚨

1. First, when it was revealed that John Doe was actually George.

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2. When Izzie and George saw each other at the elevator one last time before George died.

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3. When Izzie returned to Seattle Grace and Alex said it was best if she left and started over.

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4. When Demi Lovato guest-starred as a patient who was incorrectly diagnosed with paranoid schizophrenia.

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5. When Derek was shot during the hospital-shooting episode.

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6. And then when Cristina had to operate on him while being held at gunpoint, and Meredith had a miscarriage while operating on Owen.

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7. When Bailey tried desperately to save Charles, but in the end she couldn't do anything to help him.

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8. When Cristina and Owen got married at Meredith's house.

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9. When we learned that Mary, played by Mandy Moore, survived the hospital shooting, only to die several months later following a routine surgery.

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10. When Callie and Arizona were in a massive car accident and it resulted in the musical episode.

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11. When Callie and Arizona got married surrounded by all of their friends.

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12. When Meredith messed with Derek's Alzheimer's clinical trial in an effort to help Adele Webber.

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13. When Seattle Grace Mercy West played a softball game and Cristina gave us this iconic moment.

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14. When Teddy didn't tell Cristina that she was operating on Henry, and then Henry died during surgery.

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15. When Meredith and Derek officially adopted Zola.

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16. When Grey's Anatomy gave us the alternate-reality episode, which featured Alex and Meredith as a couple and Ellis Grey without Alzheimer's.

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17. When April had sex with Jackson for the first time and then failed her medical boards.

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18. When Lexie confessed that she still loved Mark and would never stop having feelings for him.

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19. When Lexie was tragically killed during the plane crash.

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20. And then when Mark succumbed to his injuries several weeks later.

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21. When Callie was forced to amputate Arizona's leg in order to save her life after the crash.

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22. When Jo arrived at Seattle Grace as a new intern and it mimicked Meredith's first day in Season 1.

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23. When Bailey married Ben on the same day that Adele died.

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24. When Seattle Grace changed its name to Grey Sloan to honor Lexie and Mark.

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25. When Jackson interrupted April and Matthew's wedding and confessed his feelings for April.

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26. And then when April ran away with Jackson and they got married.

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27. When Maggie showed up at Grey Sloan and Richard shockingly learned that she was his and Ellis's daughter.

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28. When Cristina and Meredith danced it out one last time before Cristina moved to Zurich.

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29. And then when Cristina told Meredith that Derek wasn't the sun, she was.

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30. When Callie heartbreakingly realized that she didn't want to be with Arizona anymore.

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31. When April and Jackson dealt with the tragic diagnosis and death of their first child, Samuel.

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32. When Derek died after saving a family who was injured in a car crash.

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33. When Bailey deservedly became the first woman to be chief of surgery in the history of Grey Sloan.

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34. When Callie started dating Penny, who was one of the doctors at the hospital where Derek died.

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35. When Meredith was violently attacked by a patient and suffered a broken jaw.

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36. When Meredith's first-ever patient, Katie Bryce, was readmitted at the hospital.

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37. When April learned that she was pregnant again at the same time she and Jackson got divorced.

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38. When Callie moved to NYC and Arizona agreed to share custody of Sofia.

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39. When Alex was sent to jail for beating up DeLuca after wrongly assuming that he slept with Jo.

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40. When Jo revealed to Alex that she's married and Jo Wilson isn't her real name.

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41. When Maggie's mom, Diane, heartbreakingly died from cancer.

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42. When Grey Sloan literally exploded with Stephanie and several patients trapped inside.

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43. When Owen's sister Megan was miraculously found alive after going missing while serving with the Army in Iraq.

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44. When Amelia found out that she had a brain tumor and called in Tom Koracick to operate on her.

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45. When Meredith won the Harper Avery Award during the show's monumental 300th episode.

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46. When Jo and Alex got married and the ceremony was officiated by Meredith.

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47. When Arizona decided to leave Seattle and move to NYC to be closer to Callie, who was now single.

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48. When April married Matthew in a surprise wedding ceremony and left Grey Sloan to work at a charity clinic.

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49. When Meredith and DeLuca kissed for the first time on the roof of Grey Sloan and they officially started dating.

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50. When Jo helped a sexual assault survivor feel comfortable in the hospital by lining the hallway with women.

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51. When Teddy and Owen finally got together following the birth of their daughter.

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52. When Meredith, Alex, and Richard were all fired from the hospital after they committed insurance fraud in order to save a patient.

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53. When Alex read a heartfelt letter from Cristina at Meredith's medical license hearing — the letter even referenced her final line to Meredith.

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54. Also, when several of Meredith's past patients were present at the hearing, including Katie.

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55. And finally, when Meredith officially got to keep her medical license and Bailey hired her back at Grey Sloan.

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What were your favorite Grey's Anatomy moments during the last decade? Tell us in the comments below!