TV and Movies·Posted on Nov 7, 202121 TV Relationships That Actually Happened Because The Actors Had Such Undeniable ChemistryLauren Graham and Scott Patterson's chemistry as Lorelai and Luke on Gilmore Girls was too good to ignore.by Nora DominickBuzzFeed StaffLinkFacebookPinterestTwitterMail There are some spoilers ahead! 1. Lauren Graham and Scott Patterson as Lorelai and Luke on Gilmore Girls. 2. Naya Rivera and Heather Morris as Santana and Brittany on Glee. 3. Matthew Perry and Courteney Cox as Chandler and Monica on Friends. 4. Candice King and Joseph Morgan as Caroline and Klaus on The Vampire Diaries. 5. Kat Graham and Michael Malarkey as Bonnie and Enzo on The Vampire Diaries. 6. Katie Holmes and Joshua Jackson as Joey and Pacey on Dawson's Creek. 7. Neil Patrick Harris and Cobie Smulders as Barney and Robin on How I Met Your Mother. 8. Stephen Amell and Emily Bett Rickards as Oliver and Felicity on Arrow. 9. Noel Fisher and Cameron Monaghan as Mickey and Ian on Shameless. 10. Jennifer Morrison and Colin O'Donoghue as Emma and Hook on Once Upon a Time. 11. Sara Ramirez and Jessica Capshaw as Callie and Arizona on Grey's Anatomy. 12. Emily Deschanel and David Boreanaz as Bones and Booth on Bones. 13. Erika Alexander and T.C. Carson as Maxine and Kyle on Living Single. 14. Zooey Deschanel and Jake Johnson as Jess and Nick on New Girl. 15. Julianna Margulies and George Clooney as Carol and Doug on ER. 16. Danielle Savre and Stefania Spampinato as Maya and Carina on Station 19. 17. Andrew Lincoln and Danai Gurira as Rick and Michonne on The Walking Dead. 18. Kieran Culkin and J. Smith-Cameron as Roman and Gerri on Succession. 19. Madelaine Petsch and Vanessa Morgan as Cheryl and Toni on Riverdale. 20. Troian Bellisario and Keegan Allen as Spencer and Toby on Pretty Little Liars. 21. And finally, Dylan O'Brien and Holland Roden as Stiles and Lydia on Teen Wolf. We can't fit everyone into one post, so tell us what other TV couples became canon because the actors had amazing chemistry in the comments below!