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The "Grey's Anatomy" Cast In Season 1 Vs. Season 11

♪ Nobody knows where they might end up (nobody knowwwwsss) ♪

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Shonda Rhimes' medical drama debuted on March 27, 2005, and a decade later, there are only five original cast members who've grown with the series. And they are...

Ellen Pompeo (Meredith Grey)

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Bob D’Amico / ABC

Patrick Dempsey (Derek Shepherd)

Frank Ockenfels / ABC via Getty Images
Bob D’Amico / ABC

James Pickens Jr. (Richard Webber)

Frank Ockenfels / ABC via Getty Images
Bob D’Amico / ABC

Chandra Wilson (Miranda Bailey)

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Bob D’Amico / ABC

Justin Chambers (Alex Karev)

Frank Ockenfels / ABC via Getty Images)
Bob D’Amico / ABC

You almost made it, Cristina Yang (Sandra Oh). You almost made it.

Grey's Anatomy airs on Thursdays at 8 p.m. on ABC.