Start by pursuing something you might actually want to do.
Don't send out a bunch of half-hearted cover letters.
Seek advice from friends and previous coworkers.
Always present your best self to potential employers.
Don't be afraid to stand out.
Explain why you want to be with their company.
Even if you thought you totally nailed that interview and never got a call back — it sucks, but it happens.
And, hopefully, you find your perfect match.
If all else fails, a grand gesture might do the trick.