“The introduction of Romana’s second incarnation in Destiny of the Daleks, a script credited to Terry Nation, but with several additions and alterations by script editor Douglas Adams, treats the concept of regeneration humorously. At the beginning of the serial, Romana changes bodily forms several times, rather like someone casually trying on different outfits, before deciding to take the form of Princess Astra, who had been played by Lalla Ward in the final serial of Season 16, The Armageddon Factor. This regeneration scene is controversial with some fans, as it does not conform with how regeneration is treated with regards to the Doctor or other Time Lord characters. Attempts at rationalizing Romana’s regeneration have been made in licensed spin-off media, including the Short Trips short story “The Lying Old Witch in the Wardrobe” which speculates that the TARDIS was responsible for her regeneration. The canonicity of spin-off media in the Doctor Who franchise is unclear.” I think when she was changing her regeneration she did become a man for a moment, but as the blurb points out that regeneration was strange.