1.Blanche Devereaux, Rose Nylund, Dorothy Zbornak, and Sophia Petrillo of The Golden Girls
2.Walter White and Jesse Pinkman of Breaking Bad
3.Vincent Chase and Eric Murphy of Entourage
4.Joey Tribbiani and Chandler Bing of Friends
5.Lucy Ricardo and Ethel Mertz of I Love Lucy
6.Karen Walker and Jack McFarland of Will and Grace
7.Rory and Lorelai Gilmore of Gilmore Girls
8.Jerry Seinfeld and George Costanza of Seinfeld
9.Daria Morgendorffer and Jane Lane of Daria
10.Buffy Summers and Willow Rosenberg of Buffy the Vampire Slayer
11.Dawson Leery and Joey Potter of Dawson's Creek
12.SpongeBob SquarePants and Patrick Starr of SpongeBob SquarePants
13.Shawn Spencer and Burton "Gus" Guster II of Psych
14.John "J.D." Dorian and Christopher Turk of Scrubs
15.Shawn Hunter and Cory Matthews of Boy Meets World
When the mother of all comedies ends a new comedy begins. The series premiere of Friends with Better Lives, right after the finale of How I Met Your Mother, tonight at 8/7c only on CBS.