Out of nearly 1,500 adverse events reported, about 39% were determined not to be related to the medication.
That means the majority of side effects were thought to be possibly, probably, or definitely related to the medication, including one case of depression, one case of intentional overdose, and one case of irregular heartbeat after stopping the injections.
A few limitations worth noting here: The men weren't specifically questioned about depression, anxiety, or mood swings prior to the study. And, for obvious ethical reasons, there was no placebo group in this study. Interestingly, most of the adverse events were reported at one study site in Indonesia, though the study authors do not speculate as to why that may be the case.