Oilfields were targeted by RAF jets after MPs voted to back strikes against ISIS in the area.
More than 550 people were said to be injured after at least 15 airstrikes struck a marketplace in Douma, near Damascus.
The medical charity acknowledged the presidential phone call but repeated its demands for an international body to take up the investigation into the airstrike that killed 22 people.
Abu Malik worked in one of Saddam Hussein's chemical weapons facilities before joining ISIS.
The Israel Defense Forces launched airstrikes targeting Syrian Army outposts in response to four rockets that landed in the Golan Heights. A U.N. peacekeeper and two Israeli soldiers were killed.
Officials aren’t clear whether the top ISIS commander was part of the vehicle convoy.
The airstrikes targeted leaders of the little-known terror group that the U.S. first attacked in September.
There are suggestions the government could launch air strikes as early as tonight.
A monitoring group says more strikes against militant positions took place overnight.
The suspected U.S.-led strikes killed more than a dozen ISIS militants Wednesday night, a monitoring group reported. Five civilians were also said to have been killed.
John Yoo: "Obama has adopted the same view of war powers as the Bush administration."
The strikes, which have killed six militants, were apparently aimed at killing the terrorist group's leader. It is not yet clear if he was among those killed.
A tactical boost to the opposition — but a propaganda point for Assad. The regime claims the Israelis are in league with al-Qaeda!