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Spotted.
What she's up to now: Since playing Blair, Leighton has released an album, starred in the film Country Strong, and currently plays Angie on the ABC sitcom Single Parents. She's also married to Adam Brody.
What he's up to now: Penn still acts and most recently starred in the hit Netflix series You. He's also very dedicated to activism, according to his Instagram.
What he's up to now: Ed has had roles in multiple TV shows since GG. His latest is the starring role in the BBC 2 series White Gold.
What he's up to now: Nate currently plays the Deep on the hit Amazon Prime series The Boys.
What she's up to now: After her stint as Little J, Taylor shifted her focus from acting to music. She's currently the lead singer of her band, the Pretty Reckless.
What she's up to now: Jessica still acts and most recently had roles in the Twin Peaks reboot, Shameless, and The Orville.
What she's up to now: Kelly has kept busy since playing the iconic Lily. She's still gracing our screens in new teen dramas like Dynasty and The Perfectionists.
What he's up to now: Matthew still acts and most recently starred in the superhero movie Valentine: The Dark Avenger. With that being said, Matthew is NOT very active on social media and the most recent picture I could find was taken in 2014. Tragic.
What she's up to now: Michelle continued to act after playing the mischievous Georgina Sparks. She most recently lent her voice to the animated shows Robot Chicken and Human Kind Of.
What she's up to now: Since capturing our hearts as Dorota, Zuzanna has had roles in many TV shows including Girls, The Good Wife, and Search Party.
What she's up to now: Margaret recently had a recurring role on Veep and has a role in the Netflix series The I-Land.
What she's up to now: Kaylee took a break from acting shortly after Gossip Girl wrapped. She now has three sons and is married to Michael Fitzpatrick of the band Fitz and the Tantrums, according to her Instagram.
What he's up to now: Wallace has had many roles since he played Cyrus on Gossip Girl. He recently reprised his beloved role of Rex in Pixar's Toy Story 4.
*Gossip Girl's presence was omniscient and offscreen for nearly the entire series, but she was voiced by Kristen Bell.
What she's up to now: Since her final "XOXO," Kristen has starred in Frozen, recently starred in the reboot of Veronica Mars, and currently plays Eleanor on The Good Place.