In case you're not totally caught up, Amelia has been dealing with fostering Betty, a teenage mother and addict, and trying to navigate her complicated relationship with Owen.
While ABC is keeping things pretty secretive about what exactly brings Kathleen to Grey-Sloan, I'm sure it's bound to be an emotional Shepherd sister reunion.
Also, besides Amelia, this is the first sister we're seeing since Derek died in Season 11, which could possibly lead to a confrontation between Meredith and Kathleen because she wasn't with Derek when he died.
So, personally, I'll be stocking up on tissues and eagerly awaiting Kathleen's arrival at Grey-Sloan Memorial Hospital.