It's officially been 16 years since The Big Bang Theory premiered on CBS. The show went on to have 12 seasons and 280 episodes, and it became one of the biggest comedy series to date. So to celebrate, let's take a look back at the iconic cast members in their first movie or TV roles vs. on the show vs. in real life:
1. Johnny Galecki's first role in 1987:

Johnny Galecki as Leonard Hofstadter on The Big Bang Theory:

Johnny Galecki now:
2. Jim Parsons's first role in 2002:

Jim Parsons as Sheldon Cooper on The Big Bang Theory:

Jim Parsons now:

3. Kaley Cuoco's first role in 1992:

Kaley Cuoco as Penny on The Big Bang Theory:

Kaley Cuoco now:

4. Simon Helberg's first role in 1999:

Simon Helberg as Howard Wolowitz on The Big Bang Theory:

Simon Helberg now:

5. Kunal Nayyar's first notable role in 2007:

Kunal Nayyar as Raj Koothrappali on The Big Bang Theory:

Kunal Nayyar now:
6. Melissa Rauch's first role in 2006:

Melissa Rauch as Bernadette Rostenkowski-Wolowitz on The Big Bang Theory:

Melissa Rauch now:
7. Mayim Bialik's first major role in 1988:

Mayim Bialik as Amy Farrah Fowler on The Big Bang Theory:

Mayim Bialik now:

8. Kevin Sussman's first notable role in 1996:

Kevin Sussman as Stuart Bloom on The Big Bang Theory:

Kevin Sussman now:

9. Christine Baranski's first notable role in 1982:

Christine Baranski as Dr. Beverly Hofstadter on The Big Bang Theory:

Christine Baranski now:

10. Wil Wheaton's first role in 1981:

Wil Wheaton as himself on The Big Bang Theory:

Wil Wheaton now:

11. John Ross Bowie's first notable role in 2000:

John Ross Bowie as Barry Kripke on The Big Bang Theory:

John Ross Bowie now:
12. And finally, Laurie Metcalf's first notable role in 1981:

Laurie Metcalf as Mary Cooper on The Big Bang Theory:

Laurie Metcalf now:
