Bell's palsy is a condition that causes facial paralysis or weakness and is usually temporary. It's not something that George has spoken a ton about, but back in 2006, he explained that his symptoms began with milk dribbling out of his mouth at lunch.
The segment began with Jimmy reflecting on a previous appearance of guest Snoop Dogg on the show, saying, "Your book had come out and we showed a picture of you in high school. A very dapper young man."
"George, we happen to have some pictures of you. This was, I think, a little before high school," Jimmy continued. George, in response, said, "I wanna point out that my mother cut my hair."
Jimmy then pulled out a photo of George at 15, to whoops from the audience. "That's hot, right there," Snoop appeared to say.
George then interjected, "Wait, I want to point out something, because you're going to laugh and make a joke. I have Bell's palsy there and half of my face is paralyzed."
George then used his hands to cover the photo, adding, "it's a completely different face."
"Yeah! So now make your joke! Make your funny joke, come on funny man! Come on, let me give you my sad face!" George then said while laughing. "You know what, I didn't have a joke George, and you've really brought everyone down," Jimmy responded.
Jimmy then finished on an image of George in senior year, saying, "I mean, what a progression this is."