1.Brad Pitt made a cameo as Will Colbert on Friends back when he and Jennifer Aniston were married in 2001.
2.Billy Magnussen, who was dating Meghann Fahy at the time, played her character's ex-boyfriend on The Bold Type.
3.Macauley Culkin, who just got engaged to Brenda Song, guest-starred on the first season of Dollface.
4.Mila Kunis played a tourist named Vivian on her husband Ashton Kutcher's show, Two and a Half Men.
5.Ben Falcone, who's married to Melissa McCarthy, appeared briefly on Gilmore Girls (and has made cameos in several of her other projects).
6.Megan Mullally guest-starred as Tammy II, Ron's ex-wife, on Parks and Recreation. Megan has been married to Nick Offerman for 19 years.
7.Nick Offerman also starred on Megan's show, Will and Grace\ two different times as two different characters.
8.David Arquette also appeared on Friends back when he and Courteney Cox were together.
9.Amy Poehler guest-starred on Arrested Development and played the onscreen wife to her IRL husband at the time, Will Arnett.
10.Will Arnett also appeared on Amy Poehler's show, Parks and Recreation, as an MRI technician.
11.Ryan Michelle Bathe has been married to Sterling K. Brown since 2007, and she guest-starred on a few episodes of This Is Us.
12.Dax Shepard is married to Kristen Bell and played a demon on an episode of The Good Place.
13.Mary Steenbergen has been married to Ted Danson since 1995 and she also appeared on The Good Place.
14.Nancy Carell has been married to Steve Carell since 1995 and she ended up playing Carol on The Office.
15.Jill Latiano appeared opposite her husband Glenn Howerton on his show, It's Always Sunny in Philadelphia.
16.Alexis Denisof and Alyson Hannigan married in 2003, after meeting on Buffy the Vampire Slayer, then he played Sandy on Alyson's show, How I Met Your Mother.
17.David Burtka is married to Neil Patrick Harris and he also appeared on a few episodes of How I Met Your Mother.
18.Taran Killam has been married to Cobie Smulders for 10 years and he was on a few episodes of her show, How I Met Your Mother.
19.Adam Brody is married to Leighton Meester in real life and he guest-starred on her show Single Parents.
20.Torrey DeVitto played Dr. Meredith Fell on The Vampire Diaries, back when she was married to Paul Wesley.
21.Hilarie Burton Morgan is married to Jeffrey Dean Morgan and she made a cameo as Lucille on The Walking Dead.
22.Kelly Ripa is married to Mark Consuelos in real life and she played his mistress on Riverdale.
23.Danneel Ackles is married to Jensen Ackles and she appeared on a few episodes of his show Supernatural.
24.Bonnie Bartlett is married to William Daniels and played Dean Bolander on a few episodes of Boy Meets World.
25.Chris Pratt guest-starred on an episode of Mom back when he was still married to Anna Faris.
26.Andrew W.K. and Kat Dennings just got engaged and he appeared on an episode of her show, Dollface.
27.Julius Tennon has been married to Viola Davis since 2003 and he guest-starred on How to Get Away With Murder
28.Lee Kirk is married to Jenna Fisher in real life and he appeared on The Office as a lactation consultant.
29.Peter Krause has been dating Lauren Graham since 2010 and he played a guest role on Gilmore Girls: A Year in the Life.
30.Lindsay Lohan guest-starred on That '70s Show back when she was dating Wilmer Valderama.
31.Troian Bellisario is married to Patrick J. Adams and she appeared on his show, Suits.
32.Patrick J. Adams also appeared on Troian Bellisario's show Pretty Little Liars.
33.David Fumero has been married to Melissa Fumero since 2007 and he appeared on an episode of Brooklyn Nine-Nine.
34.Sarah Hyland guest-starred on Shadowhunters back when she was dating Dominic Sherwood.
35.Zach Gilford is married to Kiele Sanchez in real life and he appeared on her show, Kingdom.
36.William H. Macy has been married to Felicity Huffman for 25 years and he guest-starred on her show Sports Night.
37.Denise Richards appeared on Two and a Half Men when she was married to Charlie Sheen.
38.Talia Balsam has been married to John Slattery since 1998 and she played a guest role on his show Mad Men.
39.Finally, Julia Roberts guest-starred on an episode of Law and Order back when she was dating Benjamin Bratt.
Obviously, we can’t fit everyone in one post, but tell us YOUR favorite celebrity S.O. cameos in the comments!
