This is a box of tissues! Duh. You've probably seen these guys before when you've been disgustingly sick, suffering from allergies, crying over a breakup, and/or ALL OF THE ABOVE!
Butttt, have you ever noticed your Kleenex turn this kinda gross off-white after you've been working your way through the box?
Look at that!
Well, it turns out there's a very ~purposeful~ reason. The tissues change color to indicate that you need a new box.