During the reign of the first Queen Elizabeth, paleness became synonymous with beauty, wealth, and nobility. To achieve the ultimate pale look, women would slather on this stuff called ceruse, which was a lead-based makeup. Did I say lead, because yeah, the makeup would often eat into the wearer's face, causing abject scarring and damage.
As Giovanni Lomazzo, an author from the time period, noted, ceruse "is naturally a great drier ... women who use it about their faces, doe quickly become withered and gray headed, because this dowth so mightely drie up the naturall moysture of their flesh." Sounds...great.
In the case of Queen Elizabeth herself, she wore so much ceruse that she ended up dying from it, slowly poisoning herself over time as the lead from the cosmetic seeped into her skin.
AND THAT'S NOT ALL.
Prevailing beauty standards at the time also called for women to have small rosy mouths and bright, wide-set eyes. In order to get the bright-eyed look, women would put drops of belladonna — aka deadly nightshade — in their eyes. Side effects included headache, dizziness, nausea, and blurred vision. WHUT.