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Miley Cyrus, 50 Cent, Jennifer Aniston, And More Stars Sung Chelsea Handler Off E!

"I am delighted to lead this song with my good friend, Chelsea Hammer" —Gwen Stefani

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Watch them, plus Sandra Bullock, Selena Gomez, 50 Cent, Miley Cyrus, Jennifer Aniston, and more, sing Chelsea off below:

E! Network