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Most hematologists conceive that Chronic Myeloid Leukemia / Chronic myelogenous leukemia (CML) is the commonest leucaemia in adults in India.

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India is a big country with 1.22 billion people, the population is predicted to have more than 1.53 billion by the end of 2030 and a substantive percentage are still illiterate; Accessibility of health care is non-uniform, with healthcare facilities at equivalence with the best in the world at the the metros and non-existent to rudimentary in many rural areas where patients are at the mercy of ‘Doctors’ who still practice traditional methods. Also only a very small group of population are covered by health / medical insurance.

Most hematologists conceive that Chronic Myeloid Leukemia / Chronic myelogenous leukemia (CML) is the commonest leucaemia in adults in India. CML is a myeloproliferative disorder characterised by increased growth of the granulocytic cell line without the loss of their capacity to differentiate. Accordingly, the peripheral blood cell profile shows an increased number of granulocytes and their immature precursors, including occasional blast cells.


CML progresses through 3 stages, such as :

* Chronic phase where mature cells proliferate

* Accelerated phase where additional cytogenetic abnormalities may occur

* Blast phase immature cells rapidly proliferate.

Approximately 85% of patients are diagnosed in the chronic phase and then progress to the accelerated and blast phases after 3-5 years.

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