back to top


This information is being shown to you because the post you're viewing contains information about a drug or medical device.

We are required by the FDA to show this information to you, but we also think it's important for you to see it.

Rebif® (interferon beta-1a) is a prescription medicine used to treat adults with relapsing forms of multiple sclerosis. It contains interferon beta-1a. Rebif will not cure MS but may decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS.

Important safety information

Before taking Rebif, tell your healthcare provider about your use of alcohol and other medicines, past or current liver, thyroid, or bleeding problems, mental illness including depression and suicidal behavior, blood clots, low blood counts, or seizures (epilepsy). If you are female, let your doctor know if you are pregnant or breastfeeding or plan to get pregnant or breastfeed.

Rebif can cause serious side effects. Tell your healthcare provider right away if you experience behavioral health problems including depression and suicidal thoughts, serious allergic and skin reactions, injection site skin damage, liver problems or worsening of liver problems including liver failure. Symptoms may include changes in urine, stool, and skin color, tiredness, confusion, and bleeding. Rebif can also cause low red and white blood cell and platelet counts. Symptoms may include infections, problems with bleeding, and bruising.

Common side effects of Rebif include flu-like symptoms, injection site redness, pain, and swelling, changes in liver blood tests, and stomach pain. These are not all the possible side effects of Rebif. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.