Guests in attendance included Kourtney and Rob Kardashian, Chicago West and Tristan Thompson.
As well as Kris, Kendall and Kylie Jenner.
And of course, the whole evening ended with a classic Kar/Jenner play fight after Khloé refused to let her guests leave.
The party came just a day after Tristan continued to stoke rumours of a reconciliation with Khloé by posting a glowing tribute to her on Instagram.
"I'm wise enough now to know, you came into my life to show me just what it means to be an incredible person," he wrote alongside a photo of himself with Khloé and their daughter True. "I appreciate how I am able to learn from and grow because of you."
"I thank God for the beautiful and loving woman you are to everyone, especially our daughter True," he added. "You deserve the world Koko! True and I love you mama. Happy Birthday."
And Tristan's message went down well with both Khloé and Kim, who's come a long way since being blocked by him in 2018.
Happy birthday Khloé!
Ellie Woodward is Celebrity and Entertainment Editor for BuzzFeed UK and is based in London.