The year: 1985. The town: Washington, D.C.
I love that Devil skull mushroom cloud, and the gun with the fatty barrel is pretty ill, too.
RAP (the "Regional Addiction Prevention" program) created this poster back in the decade of decadence ostensibly to warn local folk about the dangers of dissociative anaesthetic Phencyclidine.
But I think that insane illustration actually invites trial.