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The Cast Of "Grey's Anatomy" In Their First Season Vs. Now

Seattle Grace: where the water makes you ageless.

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1. Patrick Dempsey aka Dr. Derek Shepherd

Years on the show: 2005–2015

What they've been up to: Oh, you know, just starring alongside Renée Zellweger and Colin Firth in Bridget Jones's Baby.

2. Kate Walsh aka Dr. Addison Montgomery

Years on the show: 2005–2012

What they've been up to: Since leaving Grey's Anatomy for Private Practice, Walsh has acted in shows like FX's Fargo, The Hotwives of Orlando, and Bad Judge.

3. Chandra Wilson aka Dr. Miranda Bailey

Years on the show: 2005–Present

What they've been up to: Wilson spends most of her time on Grey's, but in 2010 she starred in the drama Frankie & Alice.

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4. T.R. Knight aka Dr. George O'Malley

Years on the show: 2005–2009

What they've been up to: Since ripping out our hearts as 007, Knight has appeared in The Good Wife, 11.22.63, and When We Rise. He's also set to return to Shondaland in 2017 on Season 2 of The Catch.

5. Justin Chambers aka Dr. Alex Karev

Years on the show: 2005–Present

What they've been up to: In between filming Grey's, Chambers has worked on Broken City and Private Practice.

6. Katherine Heigl aka Dr. Izzie Stevens

Years on the show: 2005–2010

What they've been up to: Goodbye, Izzie Stevens. Hello, Life as We Know It, New Year's Eve, State of Affairs, Jenny's Wedding, and Doubt.

7. James Pickens Jr. aka Dr. Richard Webber

Years on the show: 2005–Present

What they've been up to: While starring as Webber, Pickens Jr. has worked on Private Practice, 42, and For the Love of Ruth.

8. Sandra Oh aka Dr. Cristina Yang

Years on the show: 2005–2014

What they've been up to: Since leaving Grey's with a suitcase, Oh has worked on Tammy, Shitty Boyfriends, and the upcoming season of American Crime.

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9. Isaiah Washington aka Dr. Preston Burke

Years on the show: 2005–2007 (and then an episode in 2014)

What they've been up to: Washington has starred as Thelonius Jaha on The CW's The 100 since 2014.

10. Sara Ramirez aka Dr. Callie Torres

Years on the show: 2006–2016

What they've been up to: Ramirez currently voices Queen Miranda on Sofia the First.

11. Chyler Leigh aka Dr. Lexie Grey

Years on the show: 2007–2012

What they've been up to: Unlike Lexie — sorry, too soon — Leigh is doing just fine: She currently stars on The CW's Supergirl as Alex Danvers.

12. Eric Dane aka Dr. Mark Sloan

Years on the show: 2006–2012

What they've been up to: Dane currently stars on TNT's The Last Ship.

13. Kim Raver aka Dr. Teddy Altman

Years on the show: 2009-2012

What they've been up to: Raver has appeared in NCIS: Los Angeles, Revolution, 24: Live Another Day, and Bones.

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14. Jessica Capshaw aka Dr. Arizona Robbins

Years on the show: 2009–Present

What they've been up to: Capshaw is still livin' it up as Arizona, but she did take some time out of her busy schedule to voice Duck in The Hero of Color City.

15. Jesse Williams aka Dr. Jackson Avery

Years on the show: 2009–Present

What they've been up to: While starring on Grey's, Williams has appeared in The Cabin in the Woods, Lee Daniels' The Butler, and Money.

16. Sarah Drew aka Dr. April Kepner

Years on the show: 2009–Present

What they've been up to: Drew still stars as Kepner, but during her time on Grey's, she starred in Moms' Night Out.

17. Kevin McKidd aka Dr. Owen Hunt

Years on the show: 2008–Present

What they've been up to: While filming Grey's, McKidd has voiced characters on Star Wars Rebels, Toy Story That Time Forgot, and Brave.

18. Camilla Luddington aka Dr. Jo Wilson

Years on the show: 2012–Present

What they've been up to: Before starring as Jo, Luddington was Claudette on True Blood and Lizzie on Californication.

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19. Jerrika Hinton aka Dr. Stephanie Edwards

Years on the show: 2012–Present

What they've been up to: Hinton is set to star in the upcoming TV series Here, Now and Flip the Script, as well as the films Odious and Insidious: Chapter 4.

20. Jason George aka Dr. Ben Warren

Years on the show: 2010–Present

What they've been up to: During his time as Dr. Warren, the actor has also starred in Witches of East End and Mistresses.

21. Caterina Scorsone aka Dr. Amelia Shepherd

Years on the show: 2010–Present (although she didn't regularly appear until 2014)

What they've been up to: Scorsone is still on the show, but her character was actually introduced on Private Practice from 2010 to 2013 before she made her way to Seattle.

22. And finally, Ellen Pompeo aka Dr. Meredith Grey

Years on the show: 2005–Present

What they've been up to: Honestly, she's pretty much just been rockin' it as Mer for a solid 13 years... and we hope she does for a million more.

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