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1. 30 Rock (2006–13)

2. The Affair (2014–19)

3. Alias (2001–06)

4. The Americans (2013–18)

5. The Boys (2019–)

6. Buffy the Vampire Slayer (1997–2003)

7. A Different World (1987–93)

8. Catastrophe (2015–19)

9. The Expanse (2015–)

10. Farscape (1999–2003)

11. Flack (2019–)

12. Fleabag (2016–19)

13. Good Omens (2019–)

14. Grimm (2011–17)

15. Half & Half (2002–06)

16. Hoarders (2009–)

17. House (2004–12)

18. Humans (2015–18)

19. Invincible (2021–)

20. Just Add Magic (2015–19)

21. Lorena (2019)

22. Lost in Oz (2015–18)

23. Married at First Sight (2014–)

24. The Marvelous Mrs. Maisel (2017–)

25. Moesha (1996–2001)

26. One Mississippi (2015–17)

27. Orphan Black (2013–17)

28. Panic (2021–)

29. Psych (2006–14)

30. Queer As Folk (2000–05)

31. Reading Rainbow (1983–2015)

32. RuPaul's Drag Race (2009–)

33. *September Mornings (2021–)

34. Small Axe (2020)

35. Solos (2021–)

36. Suits (2011–19)

37. Teen Wolf (2011–17)

38. Tom Clancy's Jack Ryan (2018–)

39. Transparent (2014–19)

40. The Underground Railroad (2021–)

41. Undone (2019–)

42. Upload (2020–)

43. Victoria (2016–)

44. Wayne (2019–)

45. The Wilds (2020–)

46. Workaholics (2011–17)

47. Your Honor (2020–21)

*Denotes title that has been newly added to Amazon Prime Video for July