6. “Hello-o-o, nurse!” was originally intended to be Buster Bunny’s signature catchphrase. It was dropped because it made no sense for the character.
7. Producers originally wanted Patrick Stewart to voice Brain.
10. The show was actually very popular with adults. In 1995, more than one-fifth of the viewers were 25 years or older.
14. The first and only time the Warners’ parents are shown was in the 1999 direct-to-video movie, Wakko’s Wish.
No explanation is ever given to what happened to the Warners’ parents.
15. Pinky and Brain starred in two spinoffs: Pinky and the Brain, and the less memorable, Pinky, Elmyra and the Brain.
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