1. Sebastian Shaw (X-Men)
Sebastian Shaw is a supervillain in the Marvel Universe and a regular foe of The X-Men. He is a prominent businessman with many hidden investments, and is also the member of a prominent secret society where he conspires with other prominent figures bent on world domination. He became a millionaire by the time he was thirty. Shaw’s superpower is his ability to absorb energy from attacks made against him, and use that energy to attack his foes.
2. Lex Luthor (Superman)
Lex Luthor is perhaps the most famous supervillain of all time. A white-collar criminal who has almost always lacked powers or a dual identity, Luther is a Machiavellian industrialist who often uses schemes and tricks to gain power and influence. His attempts to defeat Superman are often thwarted; however, he is able to manipulate the legal system repeatedly in order to avoid long prison terms. He once ran for and was elected President of the United States, but was removed from power by Superman, Batman and other superheroes.
3. Two Face (Batman)
Two-Face was formerly District Attorney Harvey Dent, who became Two-Face after an accident. He is constantly facing a battle in himself between good and evil, and his two separate personas. He eventually settles these disagreements with the flip of a coin. He is a former ally of Batman and Commissioner Gordon and was regarded as a fine public servant before his descent into madness.
4. Clayface (Batman)
Clayface is a recurring character in the Batman rogues gallery. Though Clayface is actually several different characters, they are united by a common ability: Shapeshifting. They can easily change everything about themselves to become whatever is needed in the situation, so they can overcome the challenges that are presented.
5. William Stryker (X-Men)
William Stryker, a reverend in the comic books, believes that mutants are an abomination to God and seeks to use his power and influence through both his church and politics to ensure that mutants are not given equal rights as humans. Despite this, he often hires or otherwise associates with mutants in order to achieve the power necessary to complete his plots.