1. The Rugrats episode "Naked Tommy" was influenced by Maurice Sendak's book In the Night Kitchen.
2. Melanie Chartoff, the voice of Didi on Rugrats, was once invited into the men's room by the show's illustrators and Didi was drawn in S&M inside the stalls. Chartoff says that Didi was "decked out in leather, with whips and chains: the whole dominatrix regalia."
3. The creator of The Ren & Stimpy Show, John Kricfalusi, was kicked off the show because the network thought the episode "Man's Best Friend" was too violent.
4. Billy West, the voice of Stimpy, is also the voice of Fry on Futurama.
5. Chuckie Finster's character and personality is based on Devo frontman Mark Mothersbaugh.
6. Mothersbaugh actually composed all the music for Rugrats.
7. Toran Caudell, Rod on 7th Heaven, is the voice actor who played Arnold on Hey Arnold.
8. Mark Hamill was actually the voice of The Joker in Batman: The Animated Series and the Hobgoblin in Spider-Man.
9. When Democratic Senator Fritz Hollings called Beavis and Butthead "Buffcoat and Beaver" the show's writers created the recurring joke where older people mispronounce their names.
10. The creator of Ed, Edd, n Eddy, Danny Antonucci, also helped produce The Smurfs.
11. Kelsey Grammar has voiced The Simpsons' Sideshow Bob since 1990.
12. Flea, the Red Hot Chili Peppers' bassist, was the voice of Donnie in The Wild Thornberrys.
13. Tim Curry, from The Rocky Horror Picture Show and Home Alone 2: Lost in New York, is actually the voice of Nigel Thornberry.
14. On Doug, Doug's sister Judy got her name from Virginia Woolf poem "Shakespeare's Sister," where Woolf says that if she had a sister, her name would have been Judith.
15. The Dinks' (Doug's neighbors) name stems from the acronym D.I.N.K., meaning "double income, no kids".
16. Doug's school's vice principal, Mr. Bone, is based on Don Knotts.
17. Constance Shulman, Yoga Jones in Orange Is the New Black, is the voice of Patti Mayonnaise.
18. Space Ghost from Space Ghost Coast to Coast is actually based on a 1966 cartoon Space Ghost and Dino Boy.
19. The show's creator, Mike Lazzo, began Cartoon Network's Adult Swim and Toonami, which brought anime into the American mainstream, and the What A Cartoon show, the launching pad for Dexter's Laboratory, The Powerpuff Girls, Johnny Bravo, and Courage the Cowardly Dog.
20. Space Ghost Coast to Coast has rocks on Mars named after its characters Space Ghost, Zorak, Moltar, and Brak.
21. Tracy Grandstaff, the voice of Daria, is currently the vice president of Comedy Central.
22. There's a fan theory that believes SpongeBob and his friends are the result of radiation from nuclear arms testing that was performed on the Bikini Atoll in the late '40s and early '50s.
23. A restaurant in Rocko's Modern Life was renamed the Chewy Chicken because the Chokey Chicken too closely resembled masturbation.
24. Carlos Alazraqui, of Reno 911!, was actually the voice of Rocko.
25. Matt Stone and Trey Parker created Cartman based on what they thought Archie Bunker from All in the Family would have been like as a child.
26. The Ren & Stimpy Show had the following removed: a cross from the Pope's hat, a scene where the U.S. Constitution and Bill of Rights were burned, a severed head, and violent scenes where a baby punches Ren in the stomach.
27. "Onward and Upward," an episode that depicted Ren and Stimpy as bisexual, was banned from Nickelodeon and aired as the first episode of Ren & Stimpy: "Adult Party Cartoon."
28. Animaniacs once made a very inappropriate joke about Prince.
29. Casey Kasem provided the voice of Shaggy until the show's producers asked him to film a Burger King commercial. Kasem was a vegan and wanted Shaggy to be also, so he quit the show after two decades in 1995.
30. SWAT Kats: The Radical Squadron was canceled after one season despite being the No. 1 syndicated show of 1994.
31. Reboot is the first television show to be completely animated with CGI.
32. The entire show spans over the course of one week.
33. The original three Warner brothers in Animaniacs were named Yakki, Smakki, and Wakki, and they were also ducks.
34. Dot's full name is Princess Angelina Contessa Louisa Francesca Banana Banna Bo Besca the Third.
35. Voice actor Jess Harnell modeled Wakko's voice after Ringo Starr.
36. Pinky and the Brain was inspired by two producers of Tiny Toon Adventures, Tom Minton and Eddie Fitzgerald.
37. Richard Stone not only won an Emmy for the Pinky and the Brain theme song, he won seven Emmys for his work on Animaniacs, Freakazoid, and Hysteria!. Stone also wrote music for Ferris Bueller's Day Off.
38. All of the main characters in SpongeBob represent the seven deadly sins.
39. SpongeBob SquarePants creator Stephen Hillenburg based the idea of SpongeBob on The Intertidal Zone, a comic book he created in college.
40. Hillenburg, a former marine biologist, brought an aquarium into the SpongeBob pitch meeting and introduced all the characters inside the tank.
41. Tom Kenny, the voice of SpongeBob, previously starred as Heffer in Rocko's Modern Life, Dog in CatDog, and also narrated The Powerpuff Girls.
42. There's a theory that Courage of Courage the Cowardly Dog is a completely normal dog that sees the world through a dog's eyes, so all the monsters and aliens are just regular humans.