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ALF
ALF was set before the TV series, in which Gordon Shumway explained that his planet exploded. So all of those family members you get to know? Dead.
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Denver: The Last Dinosaur
Once again, he is the last of the dinosaurs. It doesn't even want to be subtle about it.
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Dino Riders
A small group of 400 humans flee from their conquered homeworld into Earths prehistoric past. 400!
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Disney's Gummi Bears
Where exactly are all the other Gummi Bears? The show says they fled the land. Sure.
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Smurfs
Gargamel was constantly trying to eat them, or at least do something to them. Either way, the villian wanted to wipe out the title characters.
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Thundercats
Aside from the Thundercats themselves, everyone else from their planet of Thundera are killed in the first episode.
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Transformers
Where do I start? How about Unicron eats planets full of robots!
Horrifying Recurring Theme In 80's Cartoons
Cartoons these days cover a variety of subjects, but there is only one subject that 80's cartoons dealt with better than any other decade. Genocide!
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